Testing Data
(Intracytoplasmic staining of Granulysin with B-L38 (green) vs isotypic control (grey) on NK-L cell line. The JM cell line is used as a negative cell line control)
Mouse anti-Human Granulysin Monoclonal Antibody | anti-GNLY antibody
Mouse Anti-Human Granulysin Monoclonal Antibody, Unconjugated Clone B-L38
Phosphate-buffered saline with 1% BSA and 0.1% sodium azide
Testing Data
(Intracytoplasmic staining of Granulysin with B-L38 (green) vs isotypic control (grey) on NK-L cell line. The JM cell line is used as a negative cell line control)
Testing Data
(Intracytoplasmic staining of Granulysin with B-L38 (green) vs isotypic control (grey) on NK-L cell line. The JM cell line is used as a negative cell line control)
NCBI and Uniprot Product Information
NCBI Description
The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Uniprot Description
GNLY: Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 2p11.2
Cellular Component: extracellular space
Biological Process: killing of cells of another organism; defense response to bacterium; cellular defense response; defense response to fungus
Research Articles on GNLY
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Product Notes
The GNLY gnly (Catalog #AAA335441) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti-Human Granulysin Monoclonal Antibody, Unconjugated Clone B-L38 reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Granulysin can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Working Dilution: Use 10 mul to label 106 cells or 100 mul of whole blood. Researchers should empirically determine the suitability of the GNLY gnly for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Granulysin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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