CCR1 blocking peptide
CCR1 Peptide - middle region
Target Description: Receptor for a C-C type chemokine. Binds to MIP-1-alpha, RANTES, and less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation.
NCBI and Uniprot Product Information
Uniprot Description
CCR1: Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1- beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation. Belongs to the G-protein coupled receptor 1 family.
Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1
Cellular Component: cell soma; external side of plasma membrane; plasma membrane
Molecular Function: C-C chemokine binding; C-C chemokine receptor activity; chemokine receptor activity; phosphoinositide phospholipase C activity; protein binding
Biological Process: calcium ion transport; cell-cell signaling; cellular calcium ion homeostasis; elevation of cytosolic calcium ion concentration; exocytosis; immune response; inflammatory response; leukocyte chemotaxis; myeloid cell differentiation; negative regulation of bone mineralization; negative regulation of innate immune response; positive regulation of calcium ion transport; positive regulation of cell migration; positive regulation of osteoclast differentiation
Research Articles on CCR1
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Product Notes
The CCR1 ccr1 (Catalog #AAA3248206) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The CCR1 Peptide - middle region reacts with Mouse and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: Synthetic peptide located within the following region: MQHRRLQSMT SIYLFNLAVS DLVFLFTLPF WIDYKLKDDW IFGDAMCKLL. It is sometimes possible for the material contained within the vial of "CCR1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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