Esrp2 blocking peptide
Esrp2 Peptide - N-terminal region
Gene Names
Esrp2; Rbm35b; 9530027K23Rik
Reactivity
Mouse, Human
Applications
Western Blot
Synonyms
Esrp2; Esrp2 Peptide - N-terminal region; Esrp2 blocking peptide
Reactivity
Mouse, Human
Form/Format
Lyophilized powder
Sequence
Synthetic peptide located within the following region: PPPPPGPDPAVDSATDPCPEPQSLVVLFGATAGALGPDLGSDETDLILLV
Sequence Length
717
Applicable Applications for Esrp2 blocking peptide
Western Blot (WB)
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Related Product Information for Esrp2 blocking peptide
This is a synthetic peptide designed for use in combination with anti-Esrp2 Antibody, made
Target Description: Esrp2 is an mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. It specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. It also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). It acts by directly binding specific sequences in mRNAs and binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Target Description: Esrp2 is an mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. It specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. It also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). It acts by directly binding specific sequences in mRNAs and binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2.
Product Categories/Family for Esrp2 blocking peptide
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
77kDa
NCBI Official Full Name
epithelial splicing regulatory protein 2
NCBI Official Synonym Full Names
epithelial splicing regulatory protein 2
NCBI Official Symbol
Esrp2
NCBI Official Synonym Symbols
Rbm35b; 9530027K23Rik
NCBI Protein Information
epithelial splicing regulatory protein 2
UniProt Protein Name
Epithelial splicing regulatory protein 2
Protein Family
UniProt Gene Name
Esrp2
UniProt Synonym Gene Names
Rbm35b
UniProt Entry Name
ESRP2_MOUSE
Uniprot Description
RBM35B: mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. Belongs to the ESRP family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding
Cellular Component: nucleoplasm; nucleus
Molecular Function: mRNA binding; nucleic acid binding; RNA binding; nucleotide binding
Biological Process: regulation of RNA splicing; RNA splicing; mRNA processing
Research Articles on Esrp2
Similar Products
Product Notes
The Esrp2 esrp2 (Catalog #AAA3228787) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The Esrp2 Peptide - N-terminal region reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's Esrp2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the Esrp2 esrp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: PPPPPGPDPA VDSATDPCPE PQSLVVLFGA TAGALGPDLG SDETDLILLV. It is sometimes possible for the material contained within the vial of "Esrp2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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