Western Blot (WB)
(Host: RabbitTarget Name: PINX1Sample Tissue: Human OVCAR-3 Whole Cell lysatesAntibody Dilution: 1ug/ml)
Rabbit anti-Human PINX1 Polyclonal Antibody | anti-PINX1 antibody
PINX1 Antibody - middle region
Western Blot (WB)
(Host: RabbitTarget Name: PINX1Sample Tissue: Human OVCAR-3 Whole Cell lysatesAntibody Dilution: 1ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: PINX1Sample Tissue: Human OVCAR-3 Whole Cell lysatesAntibody Dilution: 1ug/ml)
NCBI and Uniprot Product Information
Uniprot Description
SOX7: Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors. May be required for the survival of both hematopoietic and endothelial precursors during specification. Competes with GATA4 for binding and activation of the FGF3 promoter. Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'- AACAAT-3'.
Protein type: Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 8p23.1
Cellular Component: cytoplasm; nucleus
Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; sequence-specific DNA binding; transcription factor activity
Biological Process: regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter; negative regulation of cell proliferation; endoderm formation; positive regulation of transcription, DNA-dependent; positive regulation of caspase activity; negative regulation of transcription, DNA-dependent
Research Articles on PINX1
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Product Notes
The PINX1 sox7 (Catalog #AAA3223271) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PINX1 Antibody - middle region reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PINX1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the PINX1 sox7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: LGLGATINNE DNWIAHQDDF NQLLAELNTC HGQETTDSSD KKEKKSFSLE. It is sometimes possible for the material contained within the vial of "PINX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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