Western Blot (WB)
(WB Suggested Anti-GLYCTK Antibody Titration: 1.25ug/mlPositive Control: HepG2 cell lysate)
Rabbit GLYCTK Polyclonal Antibody | anti-GLYCTK antibody
GLYCTK antibody - N-terminal region
Western Blot (WB)
(WB Suggested Anti-GLYCTK Antibody Titration: 1.25ug/mlPositive Control: HepG2 cell lysate)
Western Blot (WB)
(WB Suggested Anti-GLYCTK Antibody Titration: 1.25ug/mlPositive Control: HepG2 cell lysate)
Target Description: Deficiency of human glycerate kinase leads to D-glycerate acidemia/D-glyceric aciduria.
NCBI and Uniprot Product Information
NCBI Description
This locus encodes a member of the glycerate kinase type-2 family. The encoded enzyme catalyzes the phosphorylation of (R)-glycerate and may be involved in serine degradation and fructose metabolism. Decreased activity of the encoded enzyme may be associated with the disease D-glyceric aciduria. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]
Uniprot Description
GLYCTK: Defects in GLYCTK are the cause of D-glyceric aciduria (D-GA). D-GA is a rare metabolic disease characterized by chronic metabolic acidosis and a highly variable clinical phenotype. Clinical features range from an encephalopathic presentation with seizures, microcephaly, severe mental retardation and early death, to milder manifestations with only speech delay or even normal development. Belongs to the glycerate kinase type-2 family. 7 isoforms of the human protein are produced by alternative splicing.
Protein type: Lipid Metabolism - glycerolipid; Carbohydrate Metabolism - glyoxylate and dicarboxylate; EC 2.7.1.31; Kinase, other; Amino Acid Metabolism - glycine, serine and threonine
Chromosomal Location of Human Ortholog: 3p21.1
Cellular Component: mitochondrion; cytoplasm
Molecular Function: protein binding; glycerate kinase activity; ATP binding
Biological Process: protein amino acid phosphorylation
Disease: D-glyceric Aciduria
Research Articles on GLYCTK
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Product Notes
The GLYCTK glyctk (Catalog #AAA3208733) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GLYCTK antibody - N-terminal region reacts with Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's GLYCTK can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the GLYCTK glyctk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: IQQLAEGLTA DDLLLVLISG GGSALLPAPI PPVTLEEKQT LTRLLAARGA. It is sometimes possible for the material contained within the vial of "GLYCTK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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