Alpha 1 Microglobulin Native Protein | AMBP native protein

Alpha 1 Microglobulin >98% Pure

Cat. Num. AAA319749

• Gene Names: AMBP; A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC
• Applications: ELISA
• Purity: >= 98% pure (SDS-PAGE).; Purified
• Synonyms: Alpha 1 Microglobulin; Alpha 1 Microglobulin >98% Pure; (A1MG) >= 98% Pure; AMBP native protein

• Host: Human
• Purity/Purification: >= 98% pure (SDS-PAGE).; Purified
• Form/Format: Liquid
• Concentration: 1.60 mg/mL (A1MG, OD280nm, E = 1.58) (varies by lot)
• Sequence Length: 151

• Applicable Applications for AMBP native protein: ELISA (EIA)
• Application Notes: Suitable for use in ELISA.
• Source: Human Urine
• Perservative: 0.05% Sodium Azide
• Buffer: 20 mM Tris Buffer, 100 mM Sodium Chloride, pH 8.0 + 0.2.
• Warning: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1-1.0%. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.; Human Fluids tested negative for HBsAg, HCV Antibody and HIV 1 and 2 Antibodies. Also tested negative by PCR for HBV, HIV 1 and HCV. No test guarantees a product to be non-infectious. All materials should be handled as if potentially infectious. Generally accepted laboratory practices appropriate for infectious materials should be employed when handling this product.
• Preparation and Storage: Store at -20 degree C. Avoid multiple freeze/thaw cycles.

Product Categories/Family for AMBP native protein

Purified Proteins and Bioactive Peptides

NCBI and Uniprot Product Information

• NCBI GI #: 579676
• NCBI GeneID: 259
• UniProt Accession #: P02760; P00977; P02759; P78491; Q2TU33; Q5TBD7; Q9UC58; Q9UDI8
• Molecular Weight: 38,999 Da
• NCBI Official Full Name: alpha-1-microglobulin, partial
• NCBI Official Synonym Full Names: alpha-1-microglobulin/bikunin precursor
• NCBI Official Symbol: AMBP
• NCBI Official Synonym Symbols: A1M; HCP; ITI; UTI; EDC1; HI30; ITIL; IATIL; ITILC
• NCBI Protein Information: protein AMBP; bikunin; uristatin; protein HC; trypstatin; uronic-acid-rich protein; growth-inhibiting protein 19; inter-alpha-trypsin inhibitor light chain; complex-forming glycoprotein heterogeneous in charge
• UniProt Protein Name: Protein AMBP
• Protein Family: Protein
• UniProt Gene Name: AMBP
• UniProt Synonym Gene Names: HCP; ITIL; Protein HC; ITI-LC
• UniProt Entry Name: AMBP_HUMAN

NCBI Description

This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008]

Uniprot Description

AMBP: Inter-alpha-trypsin inhibitor inhibits trypsin, plasmin, and lysosomal granulocytic elastase. Inhibits calcium oxalate crystallization.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 9q32-q33

Cellular Component: extracellular space; cell surface; intracellular membrane-bound organelle; extracellular region; plasma membrane

Molecular Function: serine-type endopeptidase inhibitor activity; protein binding; protein homodimerization activity; calcium oxalate binding; heme binding; IgA binding; calcium channel inhibitor activity

Biological Process: negative regulation of JNK cascade; receptor-mediated endocytosis; viral reproduction; heme catabolic process; negative regulation of immune response; protein catabolic process; female pregnancy; cell adhesion; protein-chromophore linkage