Rabbit Dopamine D1 Receptor (a.a. 9-21) Polyclonal Antibody | anti-DRD1 antibody
Rabbit anti D1 Dopamine Rec.
Specific for Dopamine D1 Receptor (amino acids 9-21). This antisera has been characterized by immunocytochemical, Western immunoblot and ELISA techniques.
Crossreactivity: D1 Dopamine Receptor (9-21) - 100%
D1 Dop
Reconstitute with 0.1ml of PBS, which contains 10mg/ml BSA, or with additional buffer for more dilute antisera.
Reconstituted: Aliquot and store at -20 degree C.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq]
Uniprot Description
Function: This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Subunit structure: Interacts with DNAJC14 via its C-terminus
By similarity. Interacts with DRD1IP.
Subcellular location: Cell membrane; Multi-pass membrane protein
By similarity. Endoplasmic reticulum membrane; Multi-pass membrane protein
By similarity. Note: Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14
Tissue specificity: Detected in caudate, nucleus accumbens and in the olfactory tubercle. Ref.1
Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
Research Articles on DRD1
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Product Notes
The DRD1 drd1 (Catalog #AAA316161) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Dopamine D1 Receptor (a.a. 9-21), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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