anti-Human Retinol Binding Protein 4 (RBP4) Monoclonal Antibody | anti-RBP4 antibody

MAb to Retinol Binding Prot. 4

Cat. Num. AAA312621

• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: >90% pure (SDS-PAGE). Protein A chromatography
• Synonyms: Retinol Binding Protein 4 (RBP4); Monoclonal Antibody; MAb to Retinol Binding Prot. 4; Monoclonal Antibody to Human Retinol Binding Protein 4 (RBP4); anti-RBP4 antibody

• Host: Host: Mouse. Hybridization of Sp 2/0 myeloma cells with spleen cells from BALB/c mice.; Source: Ascites
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1
• Clone Number: B575M
• Specificity: Retinol Binding Protein 4 (RBP4); Human plasma RBP4. Recognizes free RBP4 and RBP4 in complex with transthyretin. Reacts with apo-RBP4 and holo-RBP4.
• Purity/Purification: >90% pure (SDS-PAGE). Protein A chromatography
• Form/Format: Purified, Liquid
• Sequence Length: 201

• Applicable Applications for anti-RBP4 antibody: EIA/ELISA, Western Blot, Immunoassay Antibody Pairs
• Immunogen: Human recombinant RBP4
• Affinity Constant: Not determined
• Buffer: PBS, pH 7.4
• Preservative: 0.1% Sodium azide
• Notes: Some applications in which these products may be used are covered by patents issued and applicable in certain countries. Because purchase of these products does not include a license to perform any patented application, users of these products may
• Important Note: Centrifuge before opening to ensure complete recovery of vial contents.
• Warnings: This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
• Preparation and Storage: Store at 2 to 8 degree C.

Product Categories/Family for anti-RBP4 antibody

Monoclonal Antibodies to Cytokines and Growth Factors

NCBI and Uniprot Product Information

• NCBI GI #: 62298174
• NCBI GeneID: 5950
• UniProt Accession #: P02753; O43478; O43479; Q5VY24; Q8WWA3; Q9P178; D3DR38
• Molecular Weight: 23,010 Da
• NCBI Official Full Name: Retinol-binding protein 4
• NCBI Official Synonym Full Names: retinol binding protein 4, plasma
• NCBI Official Symbol: RBP4
• NCBI Protein Information: retinol-binding protein 4; RBP; PRBP; OTTHUMP00000020114; OTTHUMP00000020115; OTTHUMP00000020116; plasma retinol-binding protein; retinol-binding protein 4, interstitial
• UniProt Protein Name: Retinol-binding protein 4
• Protein Family: Retinol-binding protein
• UniProt Gene Name: RBP4
• UniProt Entry Name: RET4_HUMAN

NCBI Description

This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq]

Uniprot Description

Function: Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.

Subcellular location: Secreted.

Involvement in disease: Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [

MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.

Sequence similarities: Belongs to the calycin superfamily. Lipocalin family.

Mass spectrometry: Molecular mass is 21063.46±1.88 Da from positions 17 - 199. Determined by ESI. Ref.10Molecular mass is 20534 Da from positions 19 - 197. Determined by MALDI. Ref.12Molecular mass is 20162 Da from positions 19 - 194. Determined by MALDI. Ref.12

Sequence caution: The sequence AAF69622.1 differs from that shown. Reason: Erroneous initiation.