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anti-Human Leptin Monoclonal Antibody | anti-LEP antibody

MAb to Leptin

Gene Names
LEP; LEP
Reactivity
Human
Applications
ELISA
Purity
>90% pure. Protein A Sepharose chromatography. Purity is tested by electrophoresis.
Synonyms
Leptin; Monoclonal Antibody; MAb to Leptin; Monoclonal Antibody to Leptin; anti-LEP antibody
Ordering
For Research Use Only!
Host
Host: Mouse. Hybridization of Sp2/0 myeloma cells with spleen cells from Balb/c mice.
Source: Ascites
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4F12
Specificity
Leptin
Recognizes recombinant human Leptin and Leptin in human blood
Purity/Purification
>90% pure. Protein A Sepharose chromatography. Purity is tested by electrophoresis.
Form/Format
Purified, Liquid
Concentration
5.7 mg/ml (Sigma protein assay kit) (varies by lot)
Sequence Length
167
Applicable Applications for anti-LEP antibody
EIA/ELISA, Immunoassay Antibody Pairs
Application Notes
Leptin immunoassay. Tested in sandwich immunoassay with human blood samples. Recognizes antigen in human blood with high sensitivity. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have
Immunogen
Recombinant Leptin
Affinity Constant
Not determined
Buffer
PBS, pH 7.4
Preservative
0.1% Sodium azide
Warnings
This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Preparation and Storage
Store at 2 to 8 degree C.
Product Categories/Family for anti-LEP antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
18,716 Da
NCBI Official Full Name
leptin
NCBI Official Symbol
LEP
NCBI Official Synonym Symbols
LEP
NCBI Protein Information
leptin; obese; obesity factor; leptin (obesity homolog, mouse)
UniProt Protein Name
Leptin
Protein Family
UniProt Gene Name
LEP
UniProt Synonym Gene Names
OB; OBS
UniProt Entry Name
LEP_BOVIN

Uniprot Description

Function: May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.

Subcellular location: Secreted

Probable.

Sequence similarities: Belongs to the leptin family.

Research Articles on LEP

Similar Products

Product Notes

The LEP lep (Catalog #AAA311186) is an Antibody produced from Host: Mouse. Hybridization of Sp2/0 myeloma cells with spleen cells from Balb/c mice. Source: Ascites and is intended for research purposes only. The product is available for immediate purchase. The MAb to Leptin reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Leptin can be used in a range of immunoassay formats including, but not limited to, EIA/ELISA, Immunoassay Antibody Pairs. Leptin immunoassay. Tested in sandwich immunoassay with human blood samples. Recognizes antigen in human blood with high sensitivity. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have. Researchers should empirically determine the suitability of the LEP lep for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Leptin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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