Immunohistochemistry (IHC)
(Paraformaldehyde-fixed, paraffin embedded (Human pancreatic carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TBRG1) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C)
Rabbit TBRG1 Polyclonal Antibody | anti-TBRG1 antibody
TBRG1 Polyclonal Antibody
Gene Names
TBRG1; NIAM; TB-5
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit
Applications
Immunohistochemistry
Purity
affinity purified by Protein A
Synonyms
TBRG1; Polyclonal Antibody; TBRG1 Polyclonal Antibody; NIAM; Nuclear interactor of ARF and Mdm2; Transforming growth factor beta regulator 1; TBRG-1; TBRG 1; Transforming growth factor beta regulator 1.; anti-TBRG1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit
Clonality
Polyclonal
Specificity
TBRG1 Polyclonal Antibody detects endogenous levels of TBRG1 protein.
Purity/Purification
affinity purified by Protein A
Form/Format
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 145% Glycerol.
Applicable Applications for anti-TBRG1 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:100-500
Immunogen
KLH conjugated synthetic peptide derived from human TBRG1:28-130/411
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -64 degree C long term. Avoid freeze-thaw cycles.
Immunohistochemistry (IHC)
(Paraformaldehyde-fixed, paraffin embedded (Human pancreatic carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TBRG1) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C)
Immunohistochemistry (IHC)
(Paraformaldehyde-fixed, paraffin embedded (Human pancreatic carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (TBRG1) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C)
Related Product Information for anti-TBRG1 antibody
Acts as a growth inhibitor. Can activate TP53/p53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability. There are two isoforms.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
411
NCBI Official Full Name
Transforming growth factor beta regulator 1
NCBI Official Synonym Full Names
transforming growth factor beta regulator 1
NCBI Official Symbol
TBRG1
NCBI Official Synonym Symbols
NIAM; TB-5
NCBI Protein Information
transforming growth factor beta regulator 1; nuclear interactor of ARF and MDM2
UniProt Protein Name
Transforming growth factor beta regulator 1
Protein Family
UniProt Gene Name
TBRG1
UniProt Synonym Gene Names
NIAM
UniProt Entry Name
TBRG1_HUMAN
Uniprot Description
TBRG1: Acts as a growth inhibitor. Can activate p53/TP53, causes G1 arrest and collaborates with CDKN2A to restrict proliferation, but does not require either protein to inhibit DNA synthesis. Redistributes CDKN2A into the nucleoplasm. Involved in maintaining chromosomal stability. Belongs to the TBRG1 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Tumor suppressor
Chromosomal Location of Human Ortholog: 11q24.2
Cellular Component: nucleoplasm; intracellular membrane-bound organelle; nucleus
Molecular Function: protein binding
Biological Process: negative regulation of cell proliferation; nucleolus to nucleoplasm transport; protein stabilization; DNA replication; cell cycle arrest
Research Articles on TBRG1
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Product Notes
The TBRG1 tbrg1 (Catalog #AAA3015426) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TBRG1 Polyclonal Antibody reacts with Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit and may cross-react with other species as described in the data sheet. AAA Biotech's TBRG1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:100-500. Researchers should empirically determine the suitability of the TBRG1 tbrg1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TBRG1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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