Western Blot (WB)
(Western Blot (WB) analysis of Endophilin I (P84) pAb at 1:500 dilutionLane1:The Brain tissue lysate of Mouse (10ug) Lane2:The Brain tissue lysate of Rat (10ug))
Rabbit anti-Mouse, Rat Endophilin I Polyclonal Antibody | anti-P84 antibody
Endophilin I (P84) Polyclonal Antibody
Gene Names
SH3GL2; CNSA2; SH3P4; EEN-B1; SH3D2A
Reactivity
Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
Endophilin I; Polyclonal Antibody; Endophilin I (P84) Polyclonal Antibody; Endophilin-A1; EEN-B1; Endophilin-1; SH3 domain protein 2A; SH3 domain-containing GRB2-like protein 2; SH3GL2; CNSA2; SH3D2A; anti-P84 antibody
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Endophilin I (P84) polyclonal antibody detects endogenous levels of Endophilin I protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
352
Applicable Applications for anti-P84 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
Synthetic peptide, corresponding to amino acids 50-99 of Human Endophilin I.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of Endophilin I (P84) pAb at 1:500 dilutionLane1:The Brain tissue lysate of Mouse (10ug) Lane2:The Brain tissue lysate of Rat (10ug))
Western Blot (WB)
(Western Blot (WB) analysis of Endophilin I (P84) pAb at 1:500 dilutionLane1:The Brain tissue lysate of Mouse (10ug) Lane2:The Brain tissue lysate of Rat (10ug))
Related Product Information for anti-P84 antibody
The Endophilins comprise a family of three SH3 domain-containing proteins designated Endophilin I, II and III, or alternatively known as SH3P4, SH3P8 and SH3P13, respectively. These proteins associate with amphiphysin, synaptojanin and dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals. The expression patterns of the Endophilins are consistent with their cellular functions at the neuronal synapse as Endophilin I is expressed only in the brain. Both Endophilin II and Endophilin III are detected in a variety of tissues. Endophilin I is also implicated in modulating G proteincoupled receptor signaling by functioning as an adapter protein and directing beta1 adrenergic receptors to the endocytic machinery.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 40kDa
NCBI Official Full Name
endophilin-A1
NCBI Official Synonym Full Names
SH3 domain containing GRB2 like 2, endophilin A1
NCBI Official Symbol
SH3GL2
NCBI Official Synonym Symbols
CNSA2; SH3P4; EEN-B1; SH3D2A
NCBI Protein Information
endophilin-A1
UniProt Protein Name
Endophilin-A1
UniProt Gene Name
SH3GL2
UniProt Synonym Gene Names
CNSA2; SH3D2A
UniProt Entry Name
SH3G2_HUMAN
Uniprot Description
endophilin 1: Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature. Belongs to the endophilin family.
Protein type: Membrane protein, peripheral; Vesicle; Adaptor/scaffold
Chromosomal Location of Human Ortholog: 9p22
Cellular Component: Golgi membrane; plasma membrane; cytosol
Molecular Function: identical protein binding; protein binding; lipid binding
Biological Process: epidermal growth factor receptor signaling pathway; negative regulation of epidermal growth factor receptor signaling pathway; axon guidance; central nervous system development; nerve growth factor receptor signaling pathway; regulation of receptor internalization; synaptic vesicle endocytosis; antigen processing and presentation of exogenous peptide antigen via MHC class II; post-Golgi vesicle-mediated transport; signal transduction
Research Articles on P84
Similar Products
Product Notes
The P84 sh3gl2 (Catalog #AAA3013854) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Endophilin I (P84) Polyclonal Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Endophilin I can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the P84 sh3gl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Endophilin I, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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