Rabbit EPHA8 Polyclonal Antibody | anti-EPHA8 antibody

EPHA8 (Phospho-Y838) Polyclonal Antibody

Cat. Num. AAA3007902

• Gene Names: EPHA8; EEK; EK3; HEK3
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot
• Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Synonyms: EPHA8; Polyclonal Antibody; EPHA8 (Phospho-Y838) Polyclonal Antibody; Ephrin type-A receptor 8; EPH- and ELK-related kinase; EPH-like kinase 3; EK3; hEK3; Tyrosine-protein kinase receptor EEK; EEK; HEK3; KIAA1459; anti-EPHA8 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: EPHA8 (phospho-Y838) polyclonal antibody detects endogenous levels of EPHA8 protein only when phosphorylated at Tyr838.
• Purity/Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
• Form/Format: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
• Sequence Length: 495

• Applicable Applications for anti-EPHA8 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:1000
• Immunogen: Synthetic phosphopeptide derived from human EPHA8 around the phosphorylation site of Tyrosine 838.
• Preparation and Storage: Store at 4 degree C short term.; Aliquot and store at -20 degree C long term.; Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of EPHA8 (phospho-Y838) polyclonal antibody at 1:500 dilutionLane1:Hela whole cell lysate (40ug) Lane2:The Spleen tissue lysate of Mouse (40ug) Lane3:The Kidney tissue lysate of Rat (40ug))

Related Product Information for anti-EPHA8 antibody

Ephrin type-A receptor 8 is a protein that in humans is encoded by the EPHA8 gene.This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system.

NCBI and Uniprot Product Information

• NCBI GI #: 55770892
• NCBI GeneID: 2046
• NCBI Accession #: NP_001006944
• NCBI GenBank Nucleotide #: NP_001006944.1
• UniProt Accession #: P29322
• Molecular Weight: ~ 111kDa
• NCBI Official Full Name: ephrin type-A receptor 8 isoform 2
• NCBI Official Synonym Full Names: EPH receptor A8
• NCBI Official Symbol: EPHA8
• NCBI Official Synonym Symbols: EEK; EK3; HEK3
• NCBI Protein Information: ephrin type-A receptor 8
• UniProt Protein Name: Ephrin type-A receptor 8
• Protein Family: Ephrin type-A receptor
• UniProt Gene Name: EPHA8
• UniProt Synonym Gene Names: EEK; HEK3; KIAA1459; EK3; hEK3
• UniProt Entry Name: EPHA8_HUMAN

NCBI Description

This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system. [provided by RefSeq, Jul 2008]