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Western Blot (WB) (Western Blot (WB) analysis of CGA polyclonal antibody in extracts from JAR cells.)

Rabbit anti-Human, Mouse CGA Polyclonal Antibody | anti-CGA antibody

CGA Polyclonal Antibody

Gene Names
CGA; HCG; LHA; FSHA; GPA1; GPHa; TSHA; GPHA1; CG-ALPHA
Reactivity
Human, Mouse
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
CGA; Polyclonal Antibody; CGA Polyclonal Antibody; Anterior pituitary glycoprotein hormones common subunit alpha; CG alpha; CG-alpha; Choriogonadotropin Alpha Chain; Chorionic Gonadotrophin Alpha Subunit; Chorionic gonadotrophin subunit alpha; Chorionic gonadotropin alpha polypeptide; Follicle Stimulating Hormone Alpha Chain; Follicle-stimulating hormone alpha chain; Follitropin Alpha Chain; FSH Alpha; FSH-alpha; FSHA; GLHA; Glycoprotein hormones alpha chain; Glycoprotein Hormones Alpha Polypeptide; GPH Alpha; GPHa; GPHA1; HCG; LHA; L; anti-CGA antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
CGA polyclonal antibody detects endogenous levels of CGA protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
116
Applicable Applications for anti-CGA antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant full length Human CGA.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of CGA polyclonal antibody in extracts from JAR cells.)

Western Blot (WB) (Western Blot (WB) analysis of CGA polyclonal antibody in extracts from JAR cells.)
Related Product Information for anti-CGA antibody
Gonadotropin (also designated choriogonadotropin) is a hormone produced by the placenta in the first trimester of pregnancy and exists as a heterodimer formed from a common alpha chain and a unique beta chain. The unique beta chain confers biological specificity to thyrotropin, Lutropin, follitropin and gonadotropin. The secreted alpha subunit maps to human chromosome 6 and the beta subunit maps to human chromosome 19. Gonadotropin stimulates the ovaries to produce and maintain normal levels of the steroids essential for maintaining pregnancy, including estrogen and progesterone.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
~ 13kDa
NCBI Official Full Name
thyroid-stimulating hormone alpha subunit
NCBI Official Synonym Full Names
glycoprotein hormones, alpha polypeptide
NCBI Official Symbol
CGA
NCBI Official Synonym Symbols
HCG; LHA; FSHA; GPA1; GPHa; TSHA; GPHA1; CG-ALPHA
NCBI Protein Information
glycoprotein hormones alpha chain
UniProt Protein Name
Glycoprotein hormones alpha chain
Protein Family
UniProt Gene Name
CGA
UniProt Synonym Gene Names
CG-alpha; FSH-alpha; LSH-alpha; TSH-alpha
UniProt Entry Name
GLHA_HUMAN

NCBI Description

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Uniprot Description

CGA: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 6q12-q21

Cellular Component: extracellular region

Molecular Function: protein binding; hormone activity

Biological Process: cellular protein metabolic process; cell-cell signaling; peptide hormone processing; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; signal transduction; positive regulation of cell migration

Research Articles on CGA

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Product Notes

The CGA cga (Catalog #AAA3007805) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CGA Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CGA can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the CGA cga for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CGA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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