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Western Blot (WB) (Western Blot (WB) analysis of PIPOX polyclonal antibody at 1:500 dilutionLane1:HepG2 whole cell lysate (40ug) Lane2:L02 whole cell lysate (40ug) Lane3:PC12 whole cell lysate (40ug) Lane4:CT26 whole cell lysate (40ug))

Rabbit PIPOX Polyclonal Antibody | anti-PIPOX antibody

PIPOX Polyclonal Antibody

Gene Names
PIPOX; LPIPOX
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
PIPOX; Polyclonal Antibody; PIPOX Polyclonal Antibody; Peroxisomal sarcosine oxidase; PSO; L-pipecolate oxidase; L-pipecolic acid oxidase; LPIPOX; anti-PIPOX antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
PIPOX polyclonal antibody detects endogenous levels of PIPOX protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
390
Applicable Applications for anti-PIPOX antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
Synthetic peptide, corresponding Human PIPOX.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot (WB) analysis of PIPOX polyclonal antibody at 1:500 dilutionLane1:HepG2 whole cell lysate (40ug) Lane2:L02 whole cell lysate (40ug) Lane3:PC12 whole cell lysate (40ug) Lane4:CT26 whole cell lysate (40ug))

Western Blot (WB) (Western Blot (WB) analysis of PIPOX polyclonal antibody at 1:500 dilutionLane1:HepG2 whole cell lysate (40ug) Lane2:L02 whole cell lysate (40ug) Lane3:PC12 whole cell lysate (40ug) Lane4:CT26 whole cell lysate (40ug))
Related Product Information for anti-PIPOX antibody
PIPOX (pipecolic acid oxidase), also known as LPIPOX or PSO, is a 390 amino acid protein that localizes to the peroxisome and belongs to the MSOX/MTOX family. Existing as a monomer, PIPOX uses FAD as a cofactor to catalyze the metabolism and subsequent degradation of sarcosine, L-pipecolic acid and L-proline. The gene encoding PIPOX maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1, 200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 44kDa
NCBI Official Full Name
peroxisomal sarcosine oxidase
NCBI Official Synonym Full Names
pipecolic acid and sarcosine oxidase
NCBI Official Symbol
PIPOX
NCBI Official Synonym Symbols
LPIPOX
NCBI Protein Information
peroxisomal sarcosine oxidase
UniProt Protein Name
Peroxisomal sarcosine oxidase
UniProt Gene Name
PIPOX
UniProt Synonym Gene Names
LPIPOX; PSO; PSO
UniProt Entry Name
SOX_HUMAN

Research Articles on PIPOX

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Product Notes

The PIPOX pipox (Catalog #AAA3007564) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PIPOX Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PIPOX can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the PIPOX pipox for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PIPOX, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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