Western Blot (WB)
(Western Blot (WB) analysis of NTPCR polyclonal antibody at 1:500 dilutionLane1:HCT116 whole cell lysate (40ug) Lane2:HCC827 whole cell lysate (40ug) Lane3:L02 whole cell lysate (40ug) Lane4:SK-OVCAR3 whole cell lysate (40ug))
Rabbit NTPCR Polyclonal Antibody | anti-NTPCR antibody
NTPCR Polyclonal Antibody
Gene Names
NTPCR; THEP1; C1orf57; HCR-NTPase
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE)
Synonyms
NTPCR; Polyclonal Antibody; NTPCR Polyclonal Antibody; Cancer-related nucleoside-triphosphatase; NTPase; Nucleoside triphosphate phosphohydrolase; anti-NTPCR antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
NTPCR polyclonal antibody detects endogenous levels of NTPCR protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE)
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
190
Applicable Applications for anti-NTPCR antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
Synthetic peptide, corresponding to amino acids 145-189 of Human NTPCR
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Western Blot (WB)
(Western Blot (WB) analysis of NTPCR polyclonal antibody at 1:500 dilutionLane1:HCT116 whole cell lysate (40ug) Lane2:HCC827 whole cell lysate (40ug) Lane3:L02 whole cell lysate (40ug) Lane4:SK-OVCAR3 whole cell lysate (40ug))
Western Blot (WB)
(Western Blot (WB) analysis of NTPCR polyclonal antibody at 1:500 dilutionLane1:HCT116 whole cell lysate (40ug) Lane2:HCC827 whole cell lysate (40ug) Lane3:L02 whole cell lysate (40ug) Lane4:SK-OVCAR3 whole cell lysate (40ug))
Related Product Information for anti-NTPCR antibody
Belonging to the THEP1 NTPase family, C1orf57 (also known as nucleoside triphosphate phosphohydrolase), and its mouse homolog, 2310079N02Rik, are 190 amino acid proteins that has nucleotide phosphatase activity towards ATP, GTP, TTP, CTP and UTP. Acting as a monomer, it also hydrolyzes nucleoside diphosphates with lower efficiency. The gene encoding C1orf57 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3, 000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinson's, Gaucher disease and Usher syndrome are also associated with chromosome 1.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 21kDa
NCBI Official Full Name
cancer-related nucleoside-triphosphatase isoform 1
NCBI Official Synonym Full Names
nucleoside-triphosphatase, cancer-related
NCBI Official Symbol
NTPCR
NCBI Official Synonym Symbols
THEP1; C1orf57; HCR-NTPase
NCBI Protein Information
cancer-related nucleoside-triphosphatase
UniProt Protein Name
Cancer-related nucleoside-triphosphatase
Protein Family
UniProt Gene Name
NTPCR
UniProt Synonym Gene Names
C1orf57; NTPase
UniProt Entry Name
NTPCR_HUMAN
NCBI Description
The protein encoded by this gene is a non-specific nucleoside triphosphatase that is slow-acting in vitro. This gene is overexpressed in many tumor tissues, and while it is not essential for the cell, overexpression is cytotoxic. However, the cytotoxicity is not related to its triphosphatase activity. [provided by RefSeq, Jul 2016]
Uniprot Description
NTPCR: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. Hydrolyzes nucleoside diphosphates with lower efficiency. Belongs to the THEP1 NTPase family.
Protein type: EC 3.6.1.15; Hydrolase
Chromosomal Location of Human Ortholog: 1q42.2
Cellular Component: membrane
Molecular Function: nucleoside-triphosphatase activity; ATP binding
Biological Process: dephosphorylation
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Product Notes
The NTPCR ntpcr (Catalog #AAA3007463) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NTPCR Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NTPCR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the NTPCR ntpcr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NTPCR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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