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Defensin alpha3 Blocking Peptide | S52 blocking peptide

Defensin alpha3 (S52) Peptide

Gene Names
DEFA3; HP3; DEF3; HNP3; HP-3; HNP-3
Applications
Blocking
Purity
Synthetic peptide Defensin alpha3 (S52). (Note: the amino acid sequence is proprietary).
The purity is >98%.
Synonyms
Defensin alpha3; Defensin alpha3 (S52) Peptide; Neutrophil defensin 3; Defensin; alpha 3; HNP-3; HP-3; HP3; DEFA3; DEF3; S52 blocking peptide
Ordering
For Research Use Only!
Specificity
This peptide can be used with studies using MBS3003756 Defensin alpha3 (S52) pAb.
Purity/Purification
Synthetic peptide Defensin alpha3 (S52). (Note: the amino acid sequence is proprietary).
The purity is >98%.
Form/Format
1 mg/ml in DI water.
Sequence Length
94
Applicable Applications for S52 blocking peptide
Blocking
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.
Related Product Information for S52 blocking peptide
Defensins are a family of microbicidal and cytotoxic peptides which are made by neutrophils and are thought to be involved in host defense. Defensins are abundant in the granules of neutrophils and are also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract and vagina. There are six alpha-defensins, which are known as human neutrophil peptides (HNPs) in humans. HNP-1, 2, 3 and 4 are found in the microbicidal granules of neutrophils; HNP-5 and HNP-6 are located in Paneth cells of the intestinal tract. HNP-1 is found in the microbicidal granules of neutrophils and probably plays a role in phagocyte-mediated host defense. HNP-1, HNP-2 and HNP-3, which comprise about 30% of the total granule protein of the neutrophil, are secreted by most normal individuals. The HNP-1 protein is encoded by the a1-defensin (DEFA1) gene. HNP-3 is encoded by the a3-defensin (DEFA3) gene.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Defensin, alpha 3, neutrophil-specific
NCBI Official Synonym Full Names
defensin alpha 3
NCBI Official Symbol
DEFA3
NCBI Official Synonym Symbols
HP3; DEF3; HNP3; HP-3; HNP-3
NCBI Protein Information
neutrophil defensin 3
UniProt Protein Name
Neutrophil defensin 3
UniProt Gene Name
DEFA3
UniProt Synonym Gene Names
DEF3; HP-3; HP3; HP-2; HP2

NCBI Description

Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 1 by only one amino acid. This gene and the gene encoding defensin, alpha 1 are both subject to copy number variation. [provided by RefSeq, Oct 2014]

Uniprot Description

Defensin 2 and defensin 3 have antibiotic, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.

Research Articles on S52

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Product Notes

The S52 defa3 (Catalog #AAA3003757) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Defensin alpha3 can be used in a range of immunoassay formats including, but not limited to, Blocking. Researchers should empirically determine the suitability of the S52 defa3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Defensin alpha3, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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