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Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval.)

Rabbit DYNLL2 Polyclonal Antibody | anti-DYNLL2 antibody

DYNLL2 polyclonal antibody

Gene Names
DYNLL2; Dlc2; DNCL1B; RSPH22
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Immunofluorescence, ELISA
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
DYNLL2; Polyclonal Antibody; DYNLL2 polyclonal antibody; DLC2; Dynein light chain 2; cytoplasmic; 8 kDa dynein light chain b; DLC8b; Dynein light chain LC8-type 2; anti-DYNLL2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
Dynein LC 2 Polyclonal Antibody detects endogenous levels of Dynein LC 2 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applicable Applications for anti-DYNLL2 antibody
Immunohistochemistry-Paraffin (IHC-P), Immunofluorescence (IF)(paraffin section), ELISA (EIA)
Application Notes
IHC: 1/100-1/300
ELISA: 1/40,000
Immunogen
The antiserum was produced against synthesized peptide derived from human DYNLL2. AA range: 1-50
Function
May be involved in some aspects of dynein-related intracellular transport and motility. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
Similarity
Belongs to the dynein light chain family.
Subunit
Homodimer. Interacts with BMF. Component of the myosin V motor complex as well as the microtubular dynein motor complex. Interacts with rabies virus phosphoprotein.
Preparation and Storage
Store at 4 degee C for short term. Aliquot and store at -20 degee C long term. Avoid freeze-thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human breast cancer. Antibody was diluted at 1:100(4° overnight). High-pressure and temperature Tris-EDTA,pH8.0 was used for antigen retrieval.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
10,350 Da
NCBI Official Full Name
dynein light chain 2, cytoplasmic
NCBI Official Synonym Full Names
dynein, light chain, LC8-type 2
NCBI Official Symbol
DYNLL2
NCBI Official Synonym Symbols
Dlc2; DNCL1B; RSPH22
NCBI Protein Information
dynein light chain 2, cytoplasmic; DLC8b; radial spoke 22 homolog; 8 kDa dynein light chain b
UniProt Protein Name
Dynein light chain 2, cytoplasmic
Protein Family
UniProt Gene Name
DYNLL2
UniProt Synonym Gene Names
DLC2; DLC8b
UniProt Entry Name
DYL2_HUMAN

Uniprot Description

DYNLL2: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. Belongs to the dynein light chain family.

Protein type: Microtubule-binding; Motility/polarity/chemotaxis; Motor

Chromosomal Location of Human Ortholog: 17q22

Cellular Component: dynein complex; microtubule; centrosome; membrane; plasma membrane; myosin complex; nucleus; cytosol

Molecular Function: protein binding; cytoskeletal protein binding; motor activity

Biological Process: apoptosis; metabolic process; transport; organelle organization and biogenesis; antigen processing and presentation of exogenous peptide antigen via MHC class II; synaptic target recognition; microtubule-based process

Research Articles on DYNLL2

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Product Notes

The DYNLL2 dynll2 (Catalog #AAA3000845) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The DYNLL2 polyclonal antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's DYNLL2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P), Immunofluorescence (IF)(paraffin section), ELISA (EIA). IHC: 1/100-1/300 ELISA: 1/40,000. Researchers should empirically determine the suitability of the DYNLL2 dynll2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DYNLL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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