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MRAS / Ras-Related Protein M-Ras Recombinant Protein | MRAS recombinant protein

Human MRAS / Ras-Related Protein M-Ras Recombinant Protein

Gene Names
MRAS; NS11; M-RAs; RRAS3; R-RAS3
Applications
ELISA, Western Blot
Purity
>95% by SDS-PAGE
Synonyms
MRAS / Ras-Related Protein M-Ras; Human MRAS / Ras-Related Protein M-Ras Recombinant Protein; Ras-related protein M-Ras; Ras-related protein R-Ras3; RRAS3; MRAS recombinant protein
Ordering
Host
E Coli
Purity/Purification
>95% by SDS-PAGE
Form/Format
Liquid; 50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10% Glycerol (PH8.0)
Concentration
Reconstitution Dependent (varies by lot)
Sequence Length
208
Applicable Applications for MRAS recombinant protein
ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array
Species
Human
Tag
His
Subunit
Interacts with RGL3. Interacts (active GTP-bound form preferentially) with RGS14 (By similarity). Forms a multiprotein complex with SHOC2, Raf (RAF1) and protein phosphatase 1 (PPP1CA, PPP1CB and PPP1CC).
Entry Function
May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway.
Preparation and Storage
Store at -20 degree C. Avoid repeated freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
ras-related protein M-Ras isoform 1
NCBI Official Synonym Full Names
muscle RAS oncogene homolog
NCBI Official Symbol
MRAS
NCBI Official Synonym Symbols
NS11; M-RAs; RRAS3; R-RAS3
NCBI Protein Information
ras-related protein M-Ras
UniProt Protein Name
Ras-related protein M-Ras
Protein Family
UniProt Gene Name
MRAS
UniProt Synonym Gene Names
RRAS3
UniProt Entry Name
RASM_HUMAN

NCBI Description

This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Uniprot Description

MRas: May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway. Belongs to the small GTPase superfamily. Ras family.

Protein type: Oncoprotein; G protein, monomeric, Ras; G protein, monomeric; G protein

Chromosomal Location of Human Ortholog: 3q22.3

Cellular Component: plasma membrane

Molecular Function: GTPase activity; GTP binding; GTP-dependent protein binding

Biological Process: muscle development; metabolic process; multicellular organismal development; Ras protein signal transduction; actin cytoskeleton organization and biogenesis

Research Articles on MRAS

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Product Notes

The MRAS mras (Catalog #AAA2902590) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's MRAS / Ras-Related Protein M-Ras can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array. Researchers should empirically determine the suitability of the MRAS mras for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MRAS / Ras-Related Protein M-Ras, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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