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PDE1C / Calcium/calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1C Recombinant Protein | PDE1C recombinant protein

Human PDE1C / Calcium/calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1C Recombinant Protein

Applications
ELISA, Western Blot
Purity
>95% by SDS-PAGE
Synonyms
PDE1C / Calcium/calmodulin-Dependent 3'; 5'-Cyclic Nucleotide Phosphodiesterase 1C; Human PDE1C / Calcium/calmodulin-Dependent 3'; 5'-Cyclic Nucleotide Phosphodiesterase 1C Recombinant Protein; Calcium/calmodulin-dependent 3'; 5'-cyclic nucleotide phosphodiesterase 1C; Cam-PDE 1C; hCam-3; PDE1C recombinant protein
Ordering
Host
E Coli
Purity/Purification
>95% by SDS-PAGE
Form/Format
Liquid; 50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole, 10% Glycerol (PH8.0)
Concentration
Reconstitution Dependent (varies by lot)
Applicable Applications for PDE1C recombinant protein
ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array
Species
Human
Tag
His
Subunit
Homodimer.
Entry Function
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP.
Preparation and Storage
Store at -20 degree C. Avoid repeated freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
UniProt Protein Name
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
UniProt Gene Name
PDE1C
UniProt Synonym Gene Names
Cam-PDE 1C
UniProt Entry Name
PDE1C_HUMAN

Uniprot Description

PDE1C: Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP. Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleotide Metabolism - purine; Phosphodiesterase; EC 3.1.4.17

Chromosomal Location of Human Ortholog: 7p14.3

Cellular Component: cytosol

Molecular Function: calmodulin binding; calmodulin-dependent cyclic-nucleotide phosphodiesterase activity; metal ion binding

Biological Process: epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; metabolic process; phospholipase C activation; innate immune response; signal transduction

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Product Notes

The PDE1C pde1c (Catalog #AAA2902288) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PDE1C / Calcium/calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1C can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Antigen Protein (AP), Protein Array. Researchers should empirically determine the suitability of the PDE1C pde1c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDE1C / Calcium/calmodulin-Dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1C, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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