Typical Testing Data/Standard Curve (for reference only)
Mouse ATP-sensitive inward rectifier potassium channel 10 ELISA Kit | Kcnj10 elisa kit
Mouse ATP-sensitive inward rectifier potassium channel 10 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
Kir4.1: May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium. Defects in KCNJ10 are the cause of seizures, sensorineural deafness, ataxia, mental retardation, and electrolyte imbalance (SESAMES). A complex disorder characterized by generalized seizures with onset in infancy, delayed psychomotor development, ataxia, sensorineural hearing loss, hypokalemia, metabolic alkalosis, and hypomagnesemia. Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ10 subfamily.
Protein type: Channel, ligand-gated; Channel, potassium; Membrane protein, multi-pass; Membrane protein, integral
Cellular Component: apical plasma membrane; basolateral plasma membrane; integral to membrane; integral to plasma membrane; membrane; microvillus; plasma membrane
Molecular Function: ATP binding; ATP-activated inward rectifier potassium channel activity; identical protein binding; inward rectifier potassium channel activity; nucleotide binding; potassium channel activity; protein binding; receptor binding; voltage-gated ion channel activity
Biological Process: adult walking behavior; glutamate uptake during transmission of nerve impulse; ion transport; L-glutamate import; membrane hyperpolarization; myelination in the central nervous system; oligodendrocyte development; potassium ion homeostasis; potassium ion import; potassium ion transport; protein homotetramerization; regulation of long-term neuronal synaptic plasticity; regulation of membrane potential; regulation of resting membrane potential; regulation of sensory perception of pain; transport; visual perception
Research Articles on Kcnj10
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Product Notes
The Mouse Kcnj10 kcnj10 (Catalog #AAA2887627) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2887627 ELISA Kit recognizes Mouse Kcnj10. It is sometimes possible for the material contained within the vial of "ATP-sensitive inward rectifier potassium channel 10, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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