Typical Testing Data/Standard Curve (for reference only)
Mouse Phospholipase D2 ELISA Kit | Pld2 elisa kit
Mouse Phospholipase D2 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the phospholipase D (PLD) superfamily. The encoded protein catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. Phosphatidic acid is an essential intracellular lipid second messenger for many signaling pathways and has been implicated in a variety of physiological processes including cytoskeletal organization and cell proliferation. A similar gene in human may also function as a guanine nucleotide exchange factor (GEF) for the small GTPase Rac2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Uniprot Description
PLD2: a phosphatidylcholine-specific phospholipase D. Catalyzes the hydrolysis of PC to produce phosphatidic acid and choline. Activated as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. May function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control. Enriched in caveolae; may be involved in MEK/ERK signaling cascades induced by the VEGF/VEGFR-2/PKC-delta pathway in endothelial cells. Three alternatively spliced isoforms have been described.
Protein type: EC 3.1.4.4; Motility/polarity/chemotaxis; Lipid Metabolism - glycerophospholipid; Phospholipase; Lipid Metabolism - ether lipid
Cellular Component: brush border membrane; caveola; Golgi apparatus; lamellipodium; membrane; nucleus; plasma membrane; sarcolemma
Molecular Function: catalytic activity; hydrolase activity; phosphoinositide binding; phospholipase D activity; protein kinase C binding
Biological Process: cell motility involved in cell locomotion; G-protein coupled receptor internalization; inositol lipid-mediated signaling; lipid catabolic process; lipid metabolic process; neurite development; phosphatidic acid biosynthetic process; phospholipid catabolic process; positive regulation of cell adhesion; positive regulation of cell migration; positive regulation of mast cell degranulation; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of receptor-mediated endocytosis; receptor-mediated endocytosis; regulation of cell migration; regulation of phagocytosis; response to hydrogen peroxide; response to hypoxia; response to organic cyclic substance; response to peptide hormone stimulus
Research Articles on Pld2
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Product Notes
The Mouse Pld2 pld2 (Catalog #AAA2887264) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2887264 ELISA Kit recognizes Mouse Pld2. It is sometimes possible for the material contained within the vial of "Phospholipase D2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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