IHC (Immunohiostchemistry)
(VASP Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of VASP Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human VASP Polyclonal Antibody | anti-VASP antibody
VASP Antibody (C-term)
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
VASP, Antibody; VASP Antibody (C-term); Vasodilator-stimulated phosphoprotein; VASP; anti-VASP antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This VASP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-296 amino acids from the C-terminal region of human VASP.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
267-296
Sequence Length
380
Applicable Applications for anti-VASP antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Antigen Type
Synthetic Peptide
Crown Antibody
Yes
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(VASP Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of VASP Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(VASP Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of VASP Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(VASP Antibody (C-term) western blot analysis in HUVEC,THP-1 cell line lysates (35ug/lane).This demonstrates the VASP antibody detected the VASP protein (arrow).)
WB (Western Blot)
(VASP Antibody (C-term) western blot analysis in HUVEC,THP-1 cell line lysates (35ug/lane).This demonstrates the VASP antibody detected the VASP protein (arrow).)
Related Product Information for anti-VASP antibody
Vasodilator-stimulated phosphoprotein (VASP) is a member
of the Ena-VASP protein family. Ena-VASP family members contain an
EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E
motifs and targets Ena-VASP proteins to focal adhesions. In the
mid-region of the protein, family members have a proline-rich
domain that binds SH3 and WW domain-containing proteins. Their
C-terminal EVH2 domain mediates tetramerization and binds both G
and F actin. VASP is associated with filamentous actin formation
and likely plays a widespread role in cell adhesion and motility.
VASP may also be involved in the intracellular signaling pathways
that regulate integrin-extracellular matrix interactions. VASP is
regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
of the Ena-VASP protein family. Ena-VASP family members contain an
EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E
motifs and targets Ena-VASP proteins to focal adhesions. In the
mid-region of the protein, family members have a proline-rich
domain that binds SH3 and WW domain-containing proteins. Their
C-terminal EVH2 domain mediates tetramerization and binds both G
and F actin. VASP is associated with filamentous actin formation
and likely plays a widespread role in cell adhesion and motility.
VASP may also be involved in the intracellular signaling pathways
that regulate integrin-extracellular matrix interactions. VASP is
regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
Product Categories/Family for anti-VASP antibody
References
Barragan, P., et al. Thromb. Haemost. 104(2):410-411(2010)
Dittrich, M., et al. Arterioscler. Thromb. Vasc. Biol. 30(4):843-850(2010)
Gan, L., et al. Mol. Immunol. 47(6):1278-1282(2010)
Osmancik, P., et al. Catheter Cardiovasc Interv 75(2):158-166(2010)
Siller-Matula, J.M., et al. J. Thromb. Haemost. 8(2):351-359(2010)
Dittrich, M., et al. Arterioscler. Thromb. Vasc. Biol. 30(4):843-850(2010)
Gan, L., et al. Mol. Immunol. 47(6):1278-1282(2010)
Osmancik, P., et al. Catheter Cardiovasc Interv 75(2):158-166(2010)
Siller-Matula, J.M., et al. J. Thromb. Haemost. 8(2):351-359(2010)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39830
NCBI Official Full Name
vasodilator-stimulated phosphoprotein
NCBI Official Synonym Full Names
vasodilator-stimulated phosphoprotein
NCBI Official Symbol
VASP
NCBI Protein Information
vasodilator-stimulated phosphoprotein
UniProt Protein Name
Vasodilator-stimulated phosphoprotein
UniProt Gene Name
VASP
UniProt Synonym Gene Names
VASP
UniProt Entry Name
VASP_HUMAN
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Product Notes
The VASP vasp (Catalog #AAA288621) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 267-296. The VASP Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's VASP can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the VASP vasp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "VASP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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