Mouse Breast cancer type 2 susceptibility protein ELISA Kit | Brca2 elisa kit
Mouse Breast cancer type 2 susceptibility protein homolog ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
BRCA2: involved in double-strand break repair and/or homologous recombination. May participate in S phase checkpoint activation. Interacts with RAD51 and DSS1. Interacts with ubiquitinated FANCD2. Interacts with PALB2, enables the recombinational repair and checkpoint functions. Interacts with WDR16. Defects in BRCA2 are a cause of genetic susceptibility to breast cancer and may underlie susceptibility to uveal melanoma.
Protein type: Nuclear receptor co-regulator; DNA repair, damage; Tumor suppressor
Cellular Component: BRCA2-MAGE-D1 complex; centrosome; cytoplasm; cytoskeleton; nuclear chromosome, telomeric region; nucleoplasm; nucleus; protein complex; secretory granule
Molecular Function: DNA binding; gamma-tubulin binding; H3 histone acetyltransferase activity; H4 histone acetyltransferase activity; protease binding; protein binding; single-stranded DNA binding
Biological Process: brain development; cell aging; cell cycle; cell proliferation; centrosome duplication; chordate embryonic development; chromosome breakage; chromosome organization and biogenesis; cytokinesis; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; DNA damage response, signal transduction resulting in induction of apoptosis; DNA recombination; DNA repair; double-strand break repair; double-strand break repair via homologous recombination; female gonad development; hemopoiesis; homologous chromosome orientation during meiosis; inner cell mass cell proliferation; male meiosis I; mammary gland development; multicellular organism growth; negative regulation of mammary gland epithelial cell proliferation; nucleotide-excision repair; oocyte maturation; positive regulation of mitotic cell cycle; positive regulation of transcription, DNA-dependent; regulation of cell proliferation; regulation of cytokinesis; regulation of transcription, DNA-dependent; replication fork protection; response to DNA damage stimulus; response to gamma radiation; response to UV-C; response to X-ray; spermatogenesis
Research Articles on Brca2
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Product Notes
The Mouse Brca2 brca2 (Catalog #AAA2886159) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2886159 ELISA Kit recognizes Mouse Brca2. It is sometimes possible for the material contained within the vial of "Breast cancer type 2 susceptibility protein, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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