Mouse Laminin subunit gamma-2 ELISA Kit | Lamc2 elisa kit
Mouse Laminin subunit gamma-2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
LAMC2: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Ladsin exerts cell- scattering activity toward a wide variety of cells, including epithelial, endothelial, and fibroblastic cells. Defects in LAMC2 are a cause of epidermolysis bullosa junctional Herlitz type (H-JEB); also known as junctional epidermolysis bullosa Herlitz-Pearson type. JEB defines a group of blistering skin diseases characterized by tissue separation which occurs within the dermo-epidermal basement membrane. H-JEB is a severe, infantile and lethal form. Death occurs usually within the first six months of life. Occasionally, children survive to teens. H-JEB is marked by bullous lesions at birth and extensive denudation of skin and mucous membranes that may be hemorrhagic. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Extracellular matrix; Motility/polarity/chemotaxis; Secreted, signal peptide; Secreted
Cellular Component: basement membrane; cell cortex; extracellular region; extracellular space; laminin-2 complex; laminin-5 complex; membrane; perinuclear region of cytoplasm; proteinaceous extracellular matrix
Molecular Function: heparin binding; protein binding
Biological Process: cell adhesion
Research Articles on Lamc2
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Product Notes
The Mouse Lamc2 lamc2 (Catalog #AAA288597) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA288597 ELISA Kit recognizes Mouse Lamc2. It is sometimes possible for the material contained within the vial of "Laminin subunit gamma-2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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