IHC (Immunohistochemisry)
(FUT8 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FUT8 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit FUT8 Polyclonal Antibody | anti-FUT8 antibody
FUT8 Antibody (Center)
Reactivity
Human (Predicted Reactivity: Bovine, Mouse, Pig, Rat)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
FUT8, Antibody; FUT8 Antibody (Center); Alpha-(1,6)-fucosyltransferase; Alpha1-6FucT; Fucosyltransferase 8; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase; GDP-fucose--glycoprotein fucosyltransferase; Glycoprotein 6-alpha-L-fucosyltransferase; FUT8; anti-FUT8 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Mouse, Pig, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This FUT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-357 amino acids from the Central region of human FUT8.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.46 (varies by lot)
Sequence Positions
329-357
Sequence Length
169
Applicable Applications for anti-FUT8 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Crown Antibody
Yes
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohistochemisry)
(FUT8 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FUT8 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohistochemisry)
(FUT8 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FUT8 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(FUT8 Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the FUT8 antibody detected the FUT8 protein (arrow).)
WB (Western Blot)
(FUT8 Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the FUT8 antibody detected the FUT8 protein (arrow).)
WB (Western Blot)
(Western blot analysis of lysate from Hela cell line, using FUT8 Antibody (Center). AAA288394 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.)
WB (Western Blot)
(Western blot analysis of lysate from Hela cell line, using FUT8 Antibody (Center). AAA288394 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.)
Related Product Information for anti-FUT8 antibody
This enzyme belongs to the family of fucosyltransferases.
The product of this gene catalyzes the transfer of fucose from
GDP-fucose to N-linked type complex glycopeptides. This enzyme is
distinct from other fucosyltransferases which catalyze alpha1-2,
alpha1-3, and alpha1-4 fucose addition. The expression of this gene
may contribute to the malignancy of cancer cells and to their
invasive and metastatic capabilities. Alternatively spliced
variants encoding different isoforms have been identified.
The product of this gene catalyzes the transfer of fucose from
GDP-fucose to N-linked type complex glycopeptides. This enzyme is
distinct from other fucosyltransferases which catalyze alpha1-2,
alpha1-3, and alpha1-4 fucose addition. The expression of this gene
may contribute to the malignancy of cancer cells and to their
invasive and metastatic capabilities. Alternatively spliced
variants encoding different isoforms have been identified.
Product Categories/Family for anti-FUT8 antibody
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Wang, X., et al. J. Biochem. 145(5):643-651(2009)
Kudo, T., et al. Mol. Cancer 6, 32 (2007) :
Ihara, H., et al. Glycobiology 16(4):333-342(2006)
Ito, Y., et al. Cancer Lett. 200(2):167-172(2003)
Wang, X., et al. J. Biochem. 145(5):643-651(2009)
Kudo, T., et al. Mol. Cancer 6, 32 (2007) :
Ihara, H., et al. Glycobiology 16(4):333-342(2006)
Ito, Y., et al. Cancer Lett. 200(2):167-172(2003)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
66516
NCBI Official Full Name
alpha-(1,6)-fucosyltransferase isoform b
NCBI Official Synonym Full Names
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
NCBI Official Symbol
FUT8
NCBI Protein Information
alpha-(1,6)-fucosyltransferase
UniProt Protein Name
Alpha-(1,6)-fucosyltransferase
UniProt Gene Name
FUT8
UniProt Synonym Gene Names
Alpha1-6FucT
UniProt Entry Name
FUT8_HUMAN
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Product Notes
The FUT8 fut8 (Catalog #AAA288394) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 329-357. The FUT8 Antibody (Center) reacts with Human (Predicted Reactivity: Bovine, Mouse, Pig, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's FUT8 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the FUT8 fut8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FUT8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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