Mouse High affinity immunoglobulin gamma Fc receptor I ELISA Kit | Fcgr1 elisa kit

Mouse High affinity immunoglobulin gamma Fc receptor I ELISA Kit

Cat. Num. AAA288334

• Gene Names: Fcgr1; CD64; IGGHAFC; AI323638; AV092959; FcgammaRI
• Reactivity: Mouse
• Synonyms: High affinity immunoglobulin gamma Fc receptor I; Mouse High affinity immunoglobulin gamma Fc receptor I ELISA Kit; Fcgr1 elisa kit

• Reactivity: Mouse
• Specificity: This assay recognizes recombinant and natural mouse IgG Fc receptor I. No significant cross-reactivity or interference was observed.
• Sequence Length: 374

• Assay Type: Sandwich
• Detection Range: 31.2-2000 pg/ml
• Sensitivity: 15.74 pg/mL
• Intra-Assay CV: <=6.2%
• Inter-Assay CV: <=7.7%
• Recovery: 102%
• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for Fcgr1 elisa kit

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to IgG Fc receptor I. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated polyclonal antibody preparation specific for IgG Fc receptor I and Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain IgG Fc receptor I, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of IgG Fc receptor I in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 6753832
• NCBI GeneID: 14129
• NCBI Accession #: NP_034316.1
• NCBI GenBank Nucleotide #: NM_010186.5
• UniProt Accession #: P26151
• Molecular Weight: 44,888 Da
• NCBI Official Full Name: high affinity immunoglobulin gamma Fc receptor I
• NCBI Official Synonym Full Names: Fc receptor, IgG, high affinity I
• NCBI Official Symbol: Fcgr1
• NCBI Official Synonym Symbols: CD64; IGGHAFC; AI323638; AV092959; FcgammaRI
• NCBI Protein Information: high affinity immunoglobulin gamma Fc receptor I
• UniProt Protein Name: High affinity immunoglobulin gamma Fc receptor I
• Protein Family: High affinity immunoglobulin gamma Fc receptor
• UniProt Gene Name: Fcgr1
• UniProt Synonym Gene Names: Fcg1; IgG Fc receptor I; FcRI
• UniProt Entry Name: FCGR1_MOUSE

Uniprot Description

FCGR1A: High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Belongs to the immunoglobulin superfamily. FCGR1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Receptor, misc.; Membrane protein, integral

Cellular Component: external side of plasma membrane; integral to membrane; lipid raft; membrane; plasma membrane

Molecular Function: IgG binding; IgG receptor activity; leukotriene receptor binding

Biological Process: antibody-dependent cellular cytotoxicity; antigen processing and presentation of exogenous antigen; antigen processing and presentation of exogenous peptide antigen via MHC class I; cell surface receptor linked signal transduction; defense response to bacterium; immune system process; innate immune response; phagocytosis, engulfment; phagocytosis, recognition; positive regulation of phagocytosis; positive regulation of phagocytosis, engulfment; positive regulation of type IIa hypersensitivity; positive regulation of type III hypersensitivity; receptor-mediated endocytosis; regulation of immune response; response to bacterium