Mouse Sorbin and SH3 domain-containing protein 2 ELISA Kit | SORBS2 elisa kit

Mouse Sorbin and SH3 domain-containing protein 2 (SORBS2) ELISA Kit

Cat. Num. AAA284712

• Gene Names: Sorbs2; Argbp2; nArgBP2; mKIAA0777; A530071H08; 2010203O03Rik; 9430041O17Rik
• Reactivity: Mouse
• Synonyms: Sorbin and SH3 domain-containing protein 2; Mouse Sorbin and SH3 domain-containing protein 2 (SORBS2) ELISA Kit; ARGBP2; FLJ93447; KIAA0777; PRO0618; Arg binding protein 2|Arg/Abl interacting protein|Arg/Abl-interacting protein 2|OTTHUMP00000211726; SORBS2 elisa kit

• Reactivity: Mouse
• Specificity: This assay has high sensitivity and excellent specificity for detection of Mouse SORBS2. No significant cross-reactivity or interference between Mouse SORBS2 and analogues was observed.
• Sequence Length: 1196

• Samples: Serum, Plasma, Other biological fluids
• Assay Type: Sandwich
• Sample Volume: 1-200 uL
• Precision: Intra-assay Precision (Precision within an assay); Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.; Inter-assay Precision (Precision between assays); Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.; CV (%) = SD/meanX100; Intra-Assay: CV; Inter-Assay: CV
• Detection Wavelength: 450 nm
• Preparation and Storage: Store at 2-8 degree C.

Related Product Information for SORBS2 elisa kit

Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate SORBS2 in samples. An antibody specific for SORBS2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anySORBS2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for SORBS2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of SORBS2 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

• NCBI GI #: 894216149
• NCBI GeneID: 234214
• NCBI Accession #: NP_001297636.1
• NCBI GenBank Nucleotide #: NM_001310707.1
• UniProt Accession #: Q3UTJ2; Q3USC6; Q80TS1; Q8BJL6; Q8BJU3; Q8BLW9; Q8BX47; Q8CHU0
• Molecular Weight: 34,573 Da
• NCBI Official Full Name: sorbin and SH3 domain-containing protein 2 isoform 3
• NCBI Official Synonym Full Names: sorbin and SH3 domain containing 2
• NCBI Official Symbol: Sorbs2
• NCBI Official Synonym Symbols: Argbp2; nArgBP2; mKIAA0777; A530071H08; 2010203O03Rik; 9430041O17Rik
• NCBI Protein Information: sorbin and SH3 domain-containing protein 2
• UniProt Protein Name: Sorbin and SH3 domain-containing protein 2
• Protein Family: Sorbin and SH3 domain-containing protein
• UniProt Gene Name: Sorbs2
• UniProt Synonym Gene Names: Argbp2; Kiaa0777; ArgBP2

Uniprot Description

ArgBP2: Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 8|8 B1.1

Cellular Component: cell junction; cell projection; cell soma; cytoplasm; cytoskeleton; dendrite; membrane; plasma membrane; postsynaptic density

Molecular Function: nucleic acid binding; protein dimerization activity; protein domain specific binding; RNA binding

Biological Process: actin filament organization; cell adhesion; cell migration; Notch signaling pathway