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Mouse Borealin ELISA Kit | CDCA8 elisa kit

Mouse Borealin (CDCA8) ELISA Kit

Gene Names
Cdca8; BOR; DasraB; MESRGP; AU044747; Borealin; D4Ertd421e; 4831429J16Rik
Reactivity
Mouse
Synonyms
Borealin; Mouse Borealin (CDCA8) ELISA Kit; PESCRG3; BOR; MESRGP; Dasra B; Pluripotent embryonic stem cell-related gene 3 protein; CDCA8 elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Specificity
This assay has high sensitivity and excellent specificity for detection of Mouse CDCA8. No significant cross-reactivity or interference between Mouse CDCA8 and analogues was observed.
Sequence Length
280
Samples
Serum, Plasma, Other biological fluids
Assay Type
Sandwich
Sample Volume
1-200 uL
Precision
Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
Detection Wavelength
450 nm
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for CDCA8 elisa kit
Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate CDCA8 in samples. An antibody specific for CDCA8 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyCDCA8 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for CDCA8 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of CDCA8 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
18,856 Da
NCBI Official Full Name
borealin
NCBI Official Synonym Full Names
cell division cycle associated 8
NCBI Official Symbol
Cdca8
NCBI Official Synonym Symbols
BOR; DasraB; MESRGP; AU044747; Borealin; D4Ertd421e; 4831429J16Rik
NCBI Protein Information
borealin
UniProt Protein Name
Borealin
Protein Family
UniProt Gene Name
Cdca8

Uniprot Description

Borealin: Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment. Belongs to the borealin family.

Protein type: Cell cycle regulation; Nucleolus

Chromosomal Location of Human Ortholog: 4 D2.2|4 57.93 cM

Cellular Component: chromocenter; chromosome; chromosome, centromeric region; cytoplasm; cytoskeleton; intercellular bridge; midbody; nuclear body; nucleolus; nucleus; protein complex; spindle midzone

Molecular Function: protein binding

Biological Process: cell cycle; cell division; chromosome organization and biogenesis; mitotic metaphase plate congression; mitotic sister chromatid segregation

Research Articles on CDCA8

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Product Notes

The Mouse CDCA8 cdca8 (Catalog #AAA284539) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA284539 ELISA Kit recognizes Mouse CDCA8. It is sometimes possible for the material contained within the vial of "Borealin, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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