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Human Protein SZT2 ELISA Kit | KIAA0467 elisa kit

Human Protein SZT2 (KIAA0467) ELISA Kit

Gene Names
SZT2; SZT2A; SZT2B; EIEE18; C1orf84; KIAA0467
Reactivity
Human
Synonyms
Protein SZT2; Human Protein SZT2 (KIAA0467) ELISA Kit; KIAA0467 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
This assay has high sensitivity and excellent specificity for detection of Human KIAA0467. No significant cross-reactivity or interference between Human KIAA0467 and analogues was observed.
Sequence Length
3375
Samples
Serum, Plasma, Other biological fluids
Assay Type
Sandwich
Sample Volume
1-200 uL
Precision
Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
Detection Wavelength
450 nm
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for KIAA0467 elisa kit
Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate KIAA0467 in samples. An antibody specific for KIAA0467 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyKIAA0467 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for KIAA0467 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of KIAA0467 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
20,286 Da
NCBI Official Full Name
KICSTOR complex protein SZT2
NCBI Official Synonym Full Names
SZT2, KICSTOR complex subunit
NCBI Official Symbol
SZT2
NCBI Official Synonym Symbols
SZT2A; SZT2B; EIEE18; C1orf84; KIAA0467
NCBI Protein Information
KICSTOR complex protein SZT2; protein SZT2
UniProt Protein Name
KICSTOR complex protein SZT2
Protein Family
UniProt Gene Name
SZT2

NCBI Description

The protein encoded by this gene is expressed in the brain, predominantly in the parietal and frontal cortex as well as in dorsal root ganglia. It is localized to the peroxisome, and is implicated in resistance to oxidative stress. It likely functions by increasing superoxide dismutase (SOD) activity, but itself has no direct SOD activity. Studies in mice show that this gene confers low seizure threshold, and may also enhance epileptogenesis. [provided by RefSeq, Jun 2011]

Uniprot Description

SZT2: Involved in oxidative stress. May be involved in superoxide dismutase activity and in neuroprotective effect of peroxisomes, but has no direct dismutase activity when tested in yeast. May enhance epileptogenesis and confer low seizure threshold. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 1p34.2

Cellular Component: extracellular exosome; KICSTOR complex; lysosomal membrane; peroxisome

Biological Process: cellular response to amino acid starvation; cellular response to glucose starvation; central nervous system development; corpus callosum morphogenesis; negative regulation of TORC1 signaling; pigmentation; post-embryonic development; regulation of superoxide dismutase activity

Disease: Epileptic Encephalopathy, Early Infantile, 18

Research Articles on KIAA0467

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Product Notes

The Human KIAA0467 szt2 (Catalog #AAA282773) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA282773 ELISA Kit recognizes Human KIAA0467. It is sometimes possible for the material contained within the vial of "Protein SZT2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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