Mouse Yorkie homolog ELISA Kit | YAP1 elisa kit
Mouse Yorkie homolog (YAP1) ELISA Kit
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein which binds to the SH3 domain of the Yes proto-oncogene product, a tyrosine kinase. This protein contains a WW domain, consisting of four conserved aromatic amino acids including two tryptophan residues. This conserved WW domain is found in various structural, regulatory and signaling molecules in various species, and may play a role in protein-protein interaction. Following cellular damage, phosphorylation of this encoded protein may suppress apoptosis. This protein may be involved in malignant transformation in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2010]
Uniprot Description
YAP1: an adaptor protein that binds to HER4 and the SH3 domain of the Yes tyrosine kinase. Associates with multiple transcription factors in the nucleus, and appears to be a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus. Contains a WW domain that is found in various structural, regulatory and signaling molecules.
Protein type: Oncoprotein; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 9|9 A1
Cellular Component: cytoplasm; cytosol; membrane; nucleus; TEAD-1-YAP complex; TEAD-2-YAP complex; transcription factor complex
Molecular Function: activating transcription factor binding; chromatin binding; proline-rich region binding; protein binding; protein C-terminus binding; protein heterodimerization activity; transcription coactivator activity; transcription corepressor activity; transcription regulatory region DNA binding
Biological Process: cell morphogenesis; cell proliferation; cellular response to DNA damage stimulus; cellular response to gamma radiation; cellular response to retinoic acid; embryonic heart tube morphogenesis; keratinocyte differentiation; lateral mesoderm development; negative regulation of epithelial cell differentiation; negative regulation of extrinsic apoptotic signaling pathway; negative regulation of stem cell differentiation; notochord development; paraxial mesoderm development; positive regulation of canonical Wnt signaling pathway; positive regulation of cell proliferation; positive regulation of intracellular estrogen receptor signaling pathway; positive regulation of organ growth; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; progesterone receptor signaling pathway; protein complex assembly; regulation of cell proliferation; regulation of keratinocyte proliferation; regulation of metanephric nephron tubule epithelial cell differentiation; regulation of neurogenesis; regulation of stem cell proliferation; regulation of transcription, DNA-templated; response to progesterone; somatic stem cell maintenance; transcription, DNA-dependent; vasculogenesis
Research Articles on YAP1
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Product Notes
The Mouse YAP1 yap1 (Catalog #AAA282316) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA282316 ELISA Kit recognizes Mouse YAP1. It is sometimes possible for the material contained within the vial of "Yorkie homolog, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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