Human Platelet endothelial aggregation receptor 1 ELISA Kit | PEAR1 elisa kit
Human Platelet endothelial aggregation receptor 1 (PEAR1) ELISA Kit
Gene Names
PEAR1; JEDI; MEGF12
Reactivity
Human
Synonyms
Platelet endothelial aggregation receptor 1; Human Platelet endothelial aggregation receptor 1 (PEAR1) ELISA Kit; PEAR1 elisa kit
Reactivity
Human
Specificity
This assay has high sensitivity and excellent specificity for detection of Human PEAR1. No significant cross-reactivity or interference between Human PEAR1 and analogues was observed.
Sequence Length
1037
Samples
Serum, Plasma, Other biological fluids
Assay Type
Sandwich
Sample Volume
1-200 uL
Precision
Intra-assay Precision (Precision within an assay)
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
Detection Wavelength
450 nm
Preparation and Storage
Store at 2-8 degree C.
Related Product Information for PEAR1 elisa kit
Principle of the Assay: This assay employs a two-site sandwich ELISA to quantitate PEAR1 in samples. An antibody specific for PEAR1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyPEAR1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PEAR1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PEAR1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
110,666 Da
NCBI Official Full Name
platelet endothelial aggregation receptor 1 isoform 1
NCBI Official Synonym Full Names
platelet endothelial aggregation receptor 1
NCBI Official Symbol
PEAR1
NCBI Official Synonym Symbols
JEDI; MEGF12
NCBI Protein Information
platelet endothelial aggregation receptor 1
UniProt Protein Name
Platelet endothelial aggregation receptor 1
Protein Family
UniProt Gene Name
PEAR1
UniProt Synonym Gene Names
MEGF12; hPEAR1; Multiple EGF-like domains protein 12
NCBI Description
PEAR1 is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation (Nanda et al., 2005 [PubMed 15851471]).[supplied by OMIM, Mar 2008]
Uniprot Description
PEAR1: When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells. Belongs to the MEGF family.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 1q23.1
Cellular Component: integral component of membrane; phagocytic cup
Biological Process: negative regulation of Notch signaling pathway; recognition of apoptotic cell
Research Articles on PEAR1
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Product Notes
The Human PEAR1 pear1 (Catalog #AAA282070) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA282070 ELISA Kit recognizes Human PEAR1. It is sometimes possible for the material contained within the vial of "Platelet endothelial aggregation receptor 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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