Human Pre-mRNA-splicing factor SLU7 ELISA Kit | SLU7 elisa kit
Human Pre-mRNA-splicing factor SLU7 (SLU7) ELISA Kit
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
NCBI and Uniprot Product Information
NCBI Description
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions. [provided by RefSeq, Jul 2008]
Uniprot Description
SLU7: Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'- splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation. Belongs to the SLU7 family.
Protein type: RNA processing; RNA splicing; Spliceosome
Chromosomal Location of Human Ortholog: 5q33.3
Cellular Component: cytoplasm; cytosol; intracellular membrane-bound organelle; membrane; nuclear speck; nucleoplasm; nucleus; small nuclear ribonucleoprotein complex; spliceosomal complex
Molecular Function: pre-mRNA 3'-splice site binding; protein binding; second spliceosomal transesterification activity; zinc ion binding
Biological Process: alternative mRNA splicing, via spliceosome; intracellular protein transport; mRNA 3'-end processing; mRNA export from nucleus; mRNA splicing, via spliceosome; nuclear mRNA 3'-splice site recognition; RNA export from nucleus; RNA splicing, via transesterification reactions; termination of RNA polymerase II transcription
Research Articles on SLU7
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Product Notes
The Human SLU7 slu7 (Catalog #AAA280596) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA280596 ELISA Kit recognizes Human SLU7. It is sometimes possible for the material contained within the vial of "Pre-mRNA-splicing factor SLU7, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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