Fish Adenylyl Cyclase Associated Protein 1 ELISA Kit | CAP1 elisa kit

Fish Adenylyl Cyclase Associated Protein 1 ELISA Kit

• Gene Names: Park7; Dj1; CAP1; DJ-1; SP22
• Reactivity: Fish
• Synonyms: Adenylyl Cyclase Associated Protein 1; Fish Adenylyl Cyclase Associated Protein 1 ELISA Kit; CAP1 elisa kit

• Reactivity: Fish

• Assay Type: Sandwich
• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 3250916
• NCBI GeneID: 117287
• UniProt Accession #: O88767
• Molecular Weight: 19,974 Da
• NCBI Official Full Name: CAP1
• NCBI Official Synonym Full Names: parkinson protein 7
• NCBI Official Symbol: Park7
• NCBI Official Synonym Symbols: Dj1; CAP1; DJ-1; SP22
• NCBI Protein Information: protein DJ-1; fertility protein SP22; contraception-associated protein 1; parkinson disease protein 7 homolog; Parkinson disease (autosomal recessive, early onset) 7
• UniProt Protein Name: Protein DJ-1
• Protein Family: AP-1-like transcription factor
• UniProt Gene Name: Park7
• UniProt Synonym Gene Names: Cap1; Protein CAP1
• UniProt Entry Name: PARK7_RAT

NCBI Description

displays a specific localization pattern to the anterior-ventral surface of the equatorial segment; may play a role in sperm-egg interactions and fertilization [RGD, Feb 2006]

Uniprot Description

DJ-1: associated with autosomal recessive early onset parkinsonism. Involved in the oxidative stress response. Three cysteines in DJ-1 may be oxidized to cysteine sulphonic acid in the cellular response to H2O2. Loss of DJ-1 function may lead to neurodegeneration.

Protein type: EC 3.4.-.-; Transcription regulation; Nuclear receptor co-regulator; Tumor suppressor

Cellular Component: PML body; mitochondrion; axon; endoplasmic reticulum; cytoplasm; plasma membrane; chromatin; cytosol; mitochondrial respiratory chain complex I; nucleus; lipid raft

Molecular Function: identical protein binding; oxidoreductase activity, acting on peroxide as acceptor; protein homodimerization activity; transcription coactivator activity; mercury ion binding; transcription factor binding; mRNA binding; peptidase activity; protein binding; copper ion binding; enzyme binding; peroxiredoxin activity; androgen receptor binding; cytokine binding; double-stranded DNA binding; glyoxalase III activity; kinase binding; superoxide dismutase copper chaperone activity; single-stranded DNA binding; receptor binding

Biological Process: synaptic transmission, dopaminergic; negative regulation of protein export from nucleus; adult locomotory behavior; protein deglycosylation; membrane hyperpolarization; proteolysis; glycolate biosynthetic process; positive regulation of interleukin-8 production; regulation of mitochondrial membrane potential; negative regulation of protein amino acid phosphorylation; single fertilization; regulation of neuron apoptosis; dopamine uptake; negative regulation of neuron apoptosis; inflammatory response; negative regulation of protein binding; response to drug; mitochondrion organization and biogenesis; protein stabilization; regulation of TRAIL receptor biosynthetic process; detoxification of copper ion; positive regulation of peptidyl-serine phosphorylation; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; negative regulation of protein sumoylation; methylglyoxal catabolic process to D-lactate; membrane depolarization; fertilization; response to hydrogen peroxide; detoxification of mercury ion; regulation of inflammatory response; negative regulation of ubiquitin-protein ligase activity; hydrogen peroxide metabolic process; lactate biosynthetic process; autophagy; negative regulation of protein kinase activity; positive regulation of transcription factor activity; negative regulation of protein ubiquitination; positive regulation of transcription from RNA polymerase II promoter; response to oxidative stress; negative regulation of apoptosis