anti-SARS-COV2 COVID 19 Spike Protein Coronavirus Monoclonal Antibody | anti-COVID-19 antibody
SARS-COV/SARS-COV-2 Spike Monoclonal Antibody(2019-nCoV)
Reactivity
SARS-COV2
Applications
ELISA
Synonyms
COVID 19 Spike Protein Coronavirus; Monoclonal Antibody; SARS-COV/SARS-COV-2 Spike Monoclonal Antibody(2019-nCoV); 2019 Novel Coronavirus; Coronavirus; CoV; COVID-19 virus; HCoV-2; Human Coronavirus 2019; SARS2; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Spike; anti-COVID-19 antibody
Host
Mouse / Human
Reactivity
SARS-COV2
Clonality
Monoclonal
Isotype
IgG1
Clone Number
D001
Form/Format
0.2 um filtered solution in PBS
Applicable Applications for anti-COVID-19 antibody
ELISA (EIA)
Application Notes
ELISA: 1:5,000-1:10,000
Immunogen
Recombinant 2019-nCoV Spike/RBD Protein (RBD) [MBS2563849].
Important Note
Centrifuge before opening to ensure complete recovery of vial contents.
Preparation and Storage
Ships on blue ice and stored at -20 degree. Avoid freeze and thaw cycles.
Related Product Information for anti-COVID-19 antibody
Description
It is a chimeric monoclonal antibody combining the constant domains of the human IgG1 molecule with mouse variable regions. The variable region was obtained from a mouse immunized with purified,recombinant SARS-CoV Spike RBD Protein. The antibody was produced using recombinant antibody technology.
Background:
Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
It is a chimeric monoclonal antibody combining the constant domains of the human IgG1 molecule with mouse variable regions. The variable region was obtained from a mouse immunized with purified,recombinant SARS-CoV Spike RBD Protein. The antibody was produced using recombinant antibody technology.
Background:
Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Similar Products
Product Notes
The COVID-19 (Catalog #AAA2563837) is an Antibody produced from Mouse / Human and is intended for research purposes only. The product is available for immediate purchase. The SARS-COV/SARS-COV-2 Spike Monoclonal Antibody(2019-nCoV) reacts with SARS-COV2 and may cross-react with other species as described in the data sheet. AAA Biotech's COVID 19 Spike Protein Coronavirus can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 1:5,000-1:10,000. Researchers should empirically determine the suitability of the COVID-19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "COVID 19 Spike Protein Coronavirus, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
