Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using HHLA2 Polyclonal Antibody at dilution of 1:30(×200))
Rabbit anti-Human HHLA2 Polyclonal Antibody | anti-HHLA2 antibody
HHLA2 Polyclonal Antibody
ELISA: 1:5000-1:10000
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using HHLA2 Polyclonal Antibody at dilution of 1:30(×200))
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using HHLA2 Polyclonal Antibody at dilution of 1:30(×200))
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein ligand found on the surface of monocytes. The encoded protein is thought to regulate cell-mediated immunity by binding to a receptor on T lymphocytes and inhibiting the proliferation of these cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Uniprot Description
HHLA2: Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. Up-regulated in antigen-presenting cells in response to inflammation. Induced in dendritic cells in response to IFNG, poly(I:C) or heat-killed Listeria monocytogenes (at protein level). Interacts with TMIGD2. 2 isoforms of the human protein are produced by alternative splicing
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 3q13.13
Cellular Component: integral to membrane
Molecular Function: protein binding
Biological Process: positive regulation of cytokine production; T cell costimulation; positive regulation of activated T cell proliferation
Research Articles on HHLA2
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Product Notes
The HHLA2 hhla2 (Catalog #AAA2561876) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The HHLA2 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's HHLA2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:20-1:100 ELISA: 1:5000-1:10000. Researchers should empirically determine the suitability of the HHLA2 hhla2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HHLA2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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