Flow Cytometry (FC/FACS)
(C57BL/6 murine splenocytes are stained with Anti-Mouse CD11c Monoclonal Antibody(AF488 Conjugated) and Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody(APC Conjugated). Splenocytes stained with Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody(APC Conjugated)(Right) are used as control)
anti-Mouse CD11c Monoclonal Antibody | anti-CD11c antibody
Anti-Mouse CD11c Monoclonal Antibody (AF488 Conjugated) [N418]
Gene Names
Itgax; Cr4; N418; Cd11c; AI449405
Reactivity
Mouse
Applications
Flow Cytometry
Synonyms
CD11c; Monoclonal Antibody; Anti-Mouse CD11c Monoclonal Antibody (AF488 Conjugated) [N418]; Integrin alpha-X; Itgax; CD11 antigen-like family member C; Leukocyte adhesion receptor p150+95; anti-CD11c antibody
Host
Armenian Hamster
Reactivity
Mouse
Clonality
Monoclonal
Isotype
Armenian Hamster IgG
Clone Number
N418
Form/Format
Liquid; PBS with 0.05% Proclin300, 1% BSA
Concentration
0.5 mg/mL (varies by lot)
Applicable Applications for anti-CD11c antibody
Flow Cytometry (FC)
Important Note
Centrifuge before opening to ensure complete recovery of vial contents.
Isotype
AF488 Armenian Hamster IgG Isotype Control[PIP][Product MBS2557917]
Conjugation
AF488
Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined forindividual use. We suggest each investigator should titrate the reagent to obtain optimal results or refer to the dilution weused in the experiment.
Preparation and Storage
Ships on blue ice.
Keep as concentrated solution.
Store at 2~8°C and protected from prolonged exposure to light.
Do not freeze.
Keep as concentrated solution.
Store at 2~8°C and protected from prolonged exposure to light.
Do not freeze.
Flow Cytometry (FC/FACS)
(C57BL/6 murine splenocytes are stained with Anti-Mouse CD11c Monoclonal Antibody(AF488 Conjugated) and Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody(APC Conjugated). Splenocytes stained with Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody(APC Conjugated)(Right) are used as control)
Flow Cytometry (FC/FACS)
(C57BL/6 murine splenocytes are stained with Anti-Mouse CD11c Monoclonal Antibody(AF488 Conjugated) and Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody(APC Conjugated). Splenocytes stained with Anti-Mouse MHC II (I-A/I-E) Monoclonal Antibody(APC Conjugated)(Right) are used as control)
Related Product Information for anti-CD11c antibody
CD11c is a 150 kD glycoprotein also known as alphaX integrin, CR4, and p150. CD11c forms a alphaXbeta2 heterodimer with beta2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The alphaXbeta2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
integrin alpha-X isoform 1
NCBI Official Synonym Full Names
integrin alpha X
NCBI Official Symbol
Itgax
NCBI Official Synonym Symbols
Cr4; N418; Cd11c; AI449405
NCBI Protein Information
integrin alpha-X
UniProt Protein Name
Integrin alpha-X
UniProt Gene Name
Itgax
UniProt Entry Name
ITAX_MOUSE
Uniprot Description
ITGAX: Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. Belongs to the integrin alpha chain family.
Protein type: Membrane protein, integral; Motility/polarity/chemotaxis
Cellular Component: cell surface; membrane; integral to membrane; integrin complex; external side of plasma membrane
Molecular Function: metal ion binding
Biological Process: integrin-mediated signaling pathway; heterotypic cell-cell adhesion; activated T cell proliferation; cell adhesion; defense response to virus
Research Articles on CD11c
Similar Products
Product Notes
The CD11c itgax (Catalog #AAA2557969) is an Antibody produced from Armenian Hamster and is intended for research purposes only. The product is available for immediate purchase. The Anti-Mouse CD11c Monoclonal Antibody (AF488 Conjugated) [N418] reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD11c can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC). Researchers should empirically determine the suitability of the CD11c itgax for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD11c, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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