TIM-1/HAVCR1 recombinant protein
Recombinant Mouse TIM-1/HAVCR1 Protein (C-His)
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
TIM-1/HAVCR1; Recombinant Mouse TIM-1/HAVCR1 Protein (C-His); Hepatitis A virus cellular receptor 1 homolog; HAVcr-1; Kidney injury molecule 1; KIM-1; T cell membrane protein 1; TIM-1; TIM-1/HAVCR1 recombinant protein
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 mum filtered solution of PBS, pH7.4.
Sequence
Tyr22-Thr212
Sequence Length
282
Species
Mouse
Endotoxin
< 1.0 EU per mug as determined by the LAL method.
Fusion Tag
C-His
Preparation and Storage
Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Related Product Information for TIM-1/HAVCR1 recombinant protein
Protein Construction: Recombinant Mouse TIM-1 is produced by our mammalian expression system and the target gene encoding Tyr22-Thr212 is expressed with a 6His tag at the C-terminus.
Background: TIM-1/KIM-1/HAVCR belongs to the immunoglobulin superfamily that cosisits 305 amino acid (aa). It is expressed by stimulated T-cells. TIM-1/KIM-1/HAVCR may play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. And may have a role in kidney injury and repair. Belongs to the T-cell and airway phenotype regulator (Tapr) locus, a single chromosomal region that confers reduced T-helper type 2 responsiveness and protects against airway hyperactivity (AHR), the hallmark of human asthma.
Background: TIM-1/KIM-1/HAVCR belongs to the immunoglobulin superfamily that cosisits 305 amino acid (aa). It is expressed by stimulated T-cells. TIM-1/KIM-1/HAVCR may play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. And may have a role in kidney injury and repair. Belongs to the T-cell and airway phenotype regulator (Tapr) locus, a single chromosomal region that confers reduced T-helper type 2 responsiveness and protects against airway hyperactivity (AHR), the hallmark of human asthma.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Molecular Mass: 21.8kDa
Actual Protein Molecular Mass: 35-50kDa
Actual Protein Molecular Mass: 35-50kDa
NCBI Official Full Name
hepatitis A virus cellular receptor 1 homolog isoform b
UniProt Protein Name
Hepatitis A virus cellular receptor 1 homolog
UniProt Gene Name
Havcr1
UniProt Synonym Gene Names
Kim1; Tim1; Timd1; HAVcr-1; KIM-1; TIMD-1; TIM-1
UniProt Entry Name
HAVR1_MOUSE
Uniprot Description
TIM-1: May play a role in T-helper cell development and the regulation of asthma and allergic diseases. Receptor for TIMD4. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus. May play a role in kidney injury and repair. Belongs to the immunoglobulin superfamily. TIM family.
Protein type: Membrane protein, integral
Cellular Component: cell surface
Molecular Function: phosphatidylserine binding; protein binding
Biological Process: positive regulation of mast cell activation
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Product Notes
The TIM-1/HAVCR1 havcr1 (Catalog #AAA2557498) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Tyr22-Thr2 12. It is sometimes possible for the material contained within the vial of "TIM-1/HAVCR1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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