Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD177 Polyclonal Antibody at dilution of 1:300.)
Rabbit anti-Mouse, Rat CD177 Polyclonal Antibody | anti-CD177 antibody
CD177 Polyclonal Antibody
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD177 Polyclonal Antibody at dilution of 1:300.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded mouse spleen using CD177 Polyclonal Antibody at dilution of 1:300.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded rat thymus gland using CD177 Polyclonal Antibody at dilution of 1:300.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded rat thymus gland using CD177 Polyclonal Antibody at dilution of 1:300.)
NCBI and Uniprot Product Information
Uniprot Description
In association with beta-2 integrin heterodimer ITGAM/CD11b and ITGB2/CD18, mediates activation of TNF-alpha primed neutrophils including degranulation and superoxide production (). In addition, by preventing beta-2 integrin internalization and attenuating chemokine signaling favors adhesion over migration (). Heterophilic interaction with PECAM1 on endothelial cells plays a role in neutrophil transendothelial migration in vitro (). However, appears to be dispensable for neutrophil recruitment caused by bacterial infection in vivo (PubMed:25359465). Acts as a receptor for the mature form of protease PRTN3 allowing its display at the cell surface of neutrophils (). By displaying PRTN3 at the neutrophil cell surface, may play a role in enhancing endothelial cell junctional integrity and thus vascular integrity during neutrophil diapedesis ().
Research Articles on CD177
Similar Products
Product Notes
The CD177 cd177 (Catalog #AAA2556204) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CD177 Polyclonal Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CD177 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:500-1:1000. Researchers should empirically determine the suitability of the CD177 cd177 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD177, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
