Rat anti-Mouse CD119 Monoclonal Antibody | anti-CD119 antibody
Anti-Mouse CD119 Monoclonal Antibody (Biotin Conjugated)
Gene Names
Ifngr1; Ifgr; CD119; Ifngr; Nktar; IFN-gammaR
Reactivity
Mouse
Applications
Flow Cytometry, Functional Assay
Synonyms
CD119; Monoclonal Antibody; Anti-Mouse CD119 Monoclonal Antibody (Biotin Conjugated); Mouse CD119; Interferon gamma receptor 1; Ifngr1; IFN-gamma-R1; IFN-gamma-R-alpha; anti-CD119 antibody
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
GR-20
Form/Format
Liquid; PBS with 0.05% Proclin300, 1% BSA
Sequence Length
477
Applicable Applications for anti-CD119 antibody
Flow Cytometry (FC/FACS)
Application Notes
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is <=0.5 ug per 10e6 cells in 100 ul volume or 100 ul of whole blood.
Conjugation
Biotin
Cellular Localization
Membrane
Preparation and Storage
Store at 2-8 degree C. Protected from prolonged exposure to light.
Related Product Information for anti-CD119 antibody
CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-gammaRalpha chain. It is a class II cytokine receptor family member that serves as a IFN-gamma-binding chain associated with the IFN-gamma beta chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-gamma induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-gamma initiates and regulates a variety of immune responses.
References
1. Basu M, et al. 1988. P. Natl. Acad. Sci. USA 85:6282. 2. Codias EK, et al. 1990. J. Immunol. 144:2197.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
52,343 Da
NCBI Official Full Name
interferon gamma receptor 1
NCBI Official Synonym Full Names
interferon gamma receptor 1
NCBI Official Symbol
Ifngr1
NCBI Official Synonym Symbols
Ifgr; CD119; Ifngr; Nktar; IFN-gammaR
NCBI Protein Information
interferon gamma receptor 1
UniProt Protein Name
Interferon gamma receptor 1
UniProt Gene Name
Ifngr1
UniProt Synonym Gene Names
Ifngr; IFN-gamma receptor 1; IFN-gamma-R1; IFN-gamma-R-alphaBy similarityManual assertion inferred from sequence similarity toiUniProtKB:P15260Â (INGR1_HUMAN)
Uniprot Description
Associates with IFNGR2 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:2530582, PubMed:2532365, PubMed:2137461, PubMed:2531896, PubMed:2530216). Ligand binding stimulates activation of the JAK/STAT signaling pathway ().
Research Articles on CD119
Similar Products
Product Notes
The CD119 ifngr1 (Catalog #AAA2553980) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti-Mouse CD119 Monoclonal Antibody (Biotin Conjugated) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CD119 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS). Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is <=0.5 ug per 10e6 cells in 100 ul volume or 100 ul of whole blood. Researchers should empirically determine the suitability of the CD119 ifngr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD119, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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