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Thiamin Pyrophosphokinase 1/TPK1 Recombinant Protein | TPK1 recombinant protein

Recombinant Human Thiamin Pyrophosphokinase 1/TPK1 Protein (C-6His)

Gene Names
TPK1; PP20; HTPK1; THMD5
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
Thiamin Pyrophosphokinase 1/TPK1; Recombinant Human Thiamin Pyrophosphokinase 1/TPK1 Protein (C-6His); Thiamin pyrophosphokinase 1; hTPK1; Placental protein 20; PP20; Thiamine pyrophosphokinase 1; TPK1; TPK1 recombinant protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Supplied as a 0.2 mum filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Sequence Positions
Met1-Ser243
Sequence Length
194
Species
Human
Endotoxin
<1.0 EU per ug as determined by LAL test.
Fusion Tag
C-6His
Preparation and Storage
Store at < -20 degree C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Related Product Information for TPK1 recombinant protein
Thiamin pyrophosphokinase 1 (TPK1), belongs to the thiamine pyrophosphokinase family. TPK1 exists as a homodimer, and is detected in heart, kidney, testis, small intestine and peripheral blood leukocytes, and at very low levels in a variety of tissues. TPK1 can catalyze the phosphorylation of thiamine to thiamine pyrophosphate. It can also catalyze the phosphorylation of pyrithiamine to pyrithiamine pyrophosphate.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28.2 kDa
NCBI Official Full Name
thiamin pyrophosphokinase 1 isoform b
NCBI Official Synonym Full Names
thiamin pyrophosphokinase 1
NCBI Official Symbol
TPK1
NCBI Official Synonym Symbols
PP20; HTPK1; THMD5
NCBI Protein Information
thiamin pyrophosphokinase 1
UniProt Protein Name
Thiamin pyrophosphokinase 1
Protein Family
UniProt Gene Name
TPK1
UniProt Synonym Gene Names
hTPK1; PP20

NCBI Description

The protein encoded by this gene functions as a homodimer and catalyzes the conversion of thiamine to thiamine pyrophosphate, a cofactor for some enzymes of the glycolytic and energy production pathways. Defects in this gene are a cause of thiamine metabolism dysfunction syndrome-5. [provided by RefSeq, Apr 2017]

Uniprot Description

Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Can also catalyze the phosphorylation of pyrithiamine to pyrithiamine pyrophosphate.

Research Articles on TPK1

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Product Notes

The TPK1 tpk1 (Catalog #AAA2553275) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Met1-Ser243. It is sometimes possible for the material contained within the vial of "Thiamin Pyrophosphokinase 1/TPK1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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