Isocitrate Dehydrogenase 1/IDH1 Recombinant Protein | IDH1 recombinant protein
Recombinant Human Isocitrate Dehydrogenase 1/IDH1 Protein (C-8His)
Gene Names
IDH1; F23E12.180; F23E12_180; IDH-I; isocitrate dehydrogenase 1; isocitrate dehydrogenase I; NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 1
Purity
>95% as determined by reducing SDS-PAGE.
Synonyms
Isocitrate Dehydrogenase 1/IDH1; Recombinant Human Isocitrate Dehydrogenase 1/IDH1 Protein (C-8His); Isocitrate Dehydrogenase [NADP] Cytoplasmic; IDH; Cytosolic NADP-Isocitrate Dehydrogenase; IDP; NADP(+)-Specific ICDH; Oxalosuccinate Decarboxylase; IDH1; PICD; IDH1 recombinant protein
Host
E Coli
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Supplied as a 0.2 mum filtered solution of 50mM Tris, 200mM NaCl, 10% Glycerol, pH 8.0.
Sequence Positions
Met1-Leu414
Sequence Length
367
Species
Human
Endotoxin
<1.0 EU per ug as determined by LAL test.
Fusion Tag
C-8His
Preparation and Storage
Store at < -20 degree C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Related Product Information for IDH1 recombinant protein
Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 exists as a homodimer, binding one magnesium or manganese ion per subunit. Mutations of IDH1 have been shown to cause metaphyseal chondromatosis with aciduria and are involved in the development of glioma IDH plays a role in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
Molecular Mass: 48.1 kDa
Actual Protein Molecular Mass: 39-54 kDa
Actual Protein Molecular Mass: 39-54 kDa
NCBI Official Full Name
isocitrate dehydrogenase 1
NCBI Official Symbol
IDH1
NCBI Official Synonym Symbols
F23E12.180; F23E12_180; IDH-I; isocitrate dehydrogenase 1; isocitrate dehydrogenase I; NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 1
NCBI Protein Information
isocitrate dehydrogenase 1
UniProt Protein Name
Isocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial
Protein Family
UniProt Gene Name
IDH1
NCBI Description
Encodes a regulatory subunit of the mitochondrially-localized NAD+- dependent isocitrate dehydrogenase.
Uniprot Description
Performs an essential role in the oxidative function of the citric acid cycle.
Research Articles on IDH1
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Product Notes
The IDH1 idh1 (Catalog #AAA2552869) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Met1-Leu414. It is sometimes possible for the material contained within the vial of "Isocitrate Dehydrogenase 1/IDH1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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