Geranylgeranyl Pyrophosphate Synthase/GGPS1 Recombinant Protein | GGPS1 recombinant protein

Recombinant Human Geranylgeranyl Pyrophosphate Synthase/GGPS1 Protein (N-6His)

Cat. Num. AAA2552716

• Gene Names: GGPS1; GGPPS; GGPPS1
• Purity: >95% as determined by reducing SDS-PAGE.
• Synonyms: Geranylgeranyl Pyrophosphate Synthase/GGPS1; Recombinant Human Geranylgeranyl Pyrophosphate Synthase/GGPS1 Protein (N-6His); Geranylgeranyl Pyrophosphate Synthase; GGPP Synthase; GGPPSase; (2E; 6E)-Farnesyl Diphosphate Synthase; Dimethylallyltranstransferase; Farnesyl Diphosphate Synthase; Farnesyltranstransferase; Geranylgeranyl Diphosphate Synthase; Geranyltranstransferase; GGPS1; GGPS1 recombinant protein

• Host: E Coli
• Purity/Purification: >95% as determined by reducing SDS-PAGE.
• Form/Format: Supplied as a 0.2 mum filtered solution of 20mM Tris HCl, 150mM NaCl, 20% Glycerol, pH 8.0.
• Sequence Positions: Met1-Glu300
• Sequence Length: 300

• Species: Human
• Endotoxin: <1.0 EU per ug as determined by LAL test.
• Fusion Tag: N-6His
• Preparation and Storage: Store at < -20 degree C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.

Related Product Information for GGPS1 recombinant protein

Geranylgeranyl pyrophosphate synthase (GGPS1) is a member of the FPP/GGPP synthase family. GGPS1 is highly expressed in testis, heart and skeletal muscle. GGPS1 is localized in the cytoplasm and has geranylgeranyl diphosphate (GGPP) synthase activity. It catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins. Other transcriptional splice variants have been found.

NCBI and Uniprot Product Information

• NCBI GI #: 83700220
• NCBI GeneID: 9453
• NCBI Accession #: NP_001032354.1
• NCBI GenBank Nucleotide #: NM_001037277.1
• UniProt Accession #: O95749; Q5T2C8; Q6NW19; A8MVQ8
• Molecular Weight: Molecular Mass: 37.0 kDa; Actual Protein Molecular Mass: 35 kDa
• NCBI Official Full Name: geranylgeranyl pyrophosphate synthase
• NCBI Official Synonym Full Names: geranylgeranyl diphosphate synthase 1
• NCBI Official Symbol: GGPS1
• NCBI Official Synonym Symbols: GGPPS; GGPPS1
• NCBI Protein Information: geranylgeranyl pyrophosphate synthase
• UniProt Protein Name: Geranylgeranyl pyrophosphate synthase
• UniProt Gene Name: GGPS1
• UniProt Synonym Gene Names: GGPP synthase; GGPPSase

NCBI Description

This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene. [provided by RefSeq, Sep 2010]

Uniprot Description

Catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.