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Cysteine-Rich Secretory Protein 3/CRISP-3/SGP28 Recombinant Protein | CRISP-3/SGP28 recombinant protein

Recombinant Human Cysteine-Rich Secretory Protein 3/CRISP-3/SGP28 Protein (C-6His)

Gene Names
CRISP3; Aeg2; CRS3; SGP28; CRISP-3; dJ442L6.3
Purity
>90% as determined by reducing SDS-PAGE.
Synonyms
Cysteine-Rich Secretory Protein 3/CRISP-3/SGP28; Recombinant Human Cysteine-Rich Secretory Protein 3/CRISP-3/SGP28 Protein (C-6His); Cysteine-Rich Secretory Protein 3; CRISP-3; Specific Granule Protein of 28 kDa; SGP28; CRISP3; CRISP-3/SGP28 recombinant protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
>90% as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 mum filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Sequence Positions
Asn21-Tyr245
Sequence Length
268
Species
Human
Endotoxin
<1.0 EU per ug as determined by LAL test.
Fusion Tag
C-6His
Preparation and Storage
Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Related Product Information for CRISP-3/SGP28 recombinant protein
Cysteine-rich secretory protein 3 (CRISP-3) is a secreted protein, containing 1 SCP domain and 1 ShKT domain.It is belongs to the CRISP family. CRISP-3 is a glycoprotein that belongs to the family of cysteine-rich secretory proteins (CRISPs) which was originally discovered in human neutrophilic granulocytes. CRISP-3 is also widely distibuted in exocrine glands (salivary glands, pancreas and prostate), eosinophilic granulocytes and to a lower level in epididymis, ovary, thymus and colon. The presence of CRISP-3 in neutrophils, eosinophils and in exocrine secretions indicates a role in innate host defense. The antibody has been raised against recombinant C-terminally truncated form of CRISP-3 and recognizes both the N-glycosylated and non-glycosylated form of the mature protein.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Molecular Mass: 26.5 kDa
Actual Protein Molecular Mass: 28 kDa
NCBI Official Full Name
cysteine-rich secretory protein 3 isoform 2
NCBI Official Synonym Full Names
cysteine rich secretory protein 3
NCBI Official Symbol
CRISP3
NCBI Official Synonym Symbols
Aeg2; CRS3; SGP28; CRISP-3; dJ442L6.3
NCBI Protein Information
cysteine-rich secretory protein 3
UniProt Protein Name
Cysteine-rich secretory protein 3
UniProt Gene Name
CRISP3
UniProt Synonym Gene Names
CRISP-3; SGP28

NCBI Description

This gene encodes a member of the cysteine-rich secretory protein (CRISP) family within the CRISP, antigen 5 and pathogenesis-related 1 proteins superfamily. The encoded protein has an N-terminal CRISP, antigen 5 and pathogenesis-related 1 proteins domain, a hinge region, and a C-terminal ion channel regulator domain. This protein contains cysteine residues, located in both the N- and C-terminal domains, that form eight disulfide bonds, a distinguishing characteristic of this family. This gene is expressed in the male reproductive tract where it plays a role in sperm function and fertilization, and the female reproductive tract where it plays a role in endometrial receptivity for embryo implantation. This gene is upregulated in certain types of prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]

Research Articles on CRISP-3/SGP28

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Product Notes

The CRISP-3/SGP28 crisp3 (Catalog #AAA2552571) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is Asn21-Tyr245. It is sometimes possible for the material contained within the vial of "Cysteine-Rich Secretory Protein 3/CRISP-3/SGP28, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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