EphA6 / EHK-2 recombinant protein
Recombinant Mouse EphA6 / EHK-2 Protein (Fc tag) (Fc tag)
Gene Names
Epha6; Ehk2; Hek12; m-ehk2
Purity
> 90 % as determined by SDS-PAGE
Synonyms
EphA6 / EHK-2; Recombinant Mouse EphA6 / EHK-2 Protein (Fc tag) (Fc tag); Epha6; Ehk2; Hek12; m-ehk2; EphA6 / EHK-2 recombinant protein
Host
Human Cells
Purity/Purification
> 90 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
1130
Application Notes
The recombinant mouse EphA6/Fc is a disulfide-linked homodimer. The reduced monomer consists of 760 amino acids and has a predicted molecular mass of 85 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm EphA6/Fc monomer is approximately 110 kDa due to glycosylation.
Predicted N Terminal
Ser 28
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C
Related Product Information for EphA6 / EHK-2 recombinant protein
A DNA sequence encoding the extracellular domain of mouse EphA6 (NP_031964.2) (Met 1-Gln 546) was fused with the Fc region of human IgG1 at the C-terminus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
116,185 Da
NCBI Official Full Name
ephrin type-A receptor 6
NCBI Official Synonym Full Names
Eph receptor A6
NCBI Official Symbol
Epha6
NCBI Official Synonym Symbols
Ehk2; Hek12; m-ehk2
NCBI Protein Information
ephrin type-A receptor 6
UniProt Protein Name
Ephrin type-A receptor 6
UniProt Gene Name
Epha6
UniProt Synonym Gene Names
Ehk-2; Ehk2; EHK-2
Uniprot Description
EphA6: Receptor tyrosine kinase which binds promiscuously GPI- anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.7.10.1; Eph family; Kinase, protein; Membrane protein, integral; Protein kinase, TK; Protein kinase, tyrosine (receptor); TK group
Chromosomal Location of Human Ortholog: 16|16 C1.3
Cellular Component: nucleoplasm
Research Articles on EphA6 / EHK-2
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Product Notes
The EphA6 / EHK-2 epha6 (Catalog #AAA2546878) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant mouse EphA6/Fc is a disulfide-linked homodimer. The reduced monomer consists of 760 amino acids and has a predicted molecular mass of 85 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm EphA6/Fc monomer is approximately 110 kDa due to glycosylation. Researchers should empirically determine the suitability of the EphA6 / EHK-2 epha6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EphA6 / EHK-2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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