SDS-PAGE
CRELD1 recombinant protein
Recombinant Mouse CRELD1 Protein (His tag)
Gene Names
Creld1; i11E7; AI843811
Purity
> 95 % as determined by SDS-PAGE
Synonyms
CRELD1; Recombinant Mouse CRELD1 Protein (His tag); CRELD1 recombinant protein
Host
Human Cells
Purity/Purification
> 95 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
420
Application Notes
The recombinant mouse CRELD1 comprises 344 amino acids and has a predicted molecular mass of 37.7 kDa. The apparent molecular mass of the protein is approximately 48 kDa in SDS-PAGE under reducing conditions.
Predicted N Terminal
Gln 30
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C
SDS-PAGE
SDS-PAGE
Related Product Information for CRELD1 recombinant protein
Background: CRELD1 is a transmembrane glycoprotein. Epidermal growth factor (EGF)-like domain exists in CRELD1. EGF-like repeats are a class of cysteine-rich domains that mediate interactions between proteins of diverse function. EGF domains are found in proteins that are either completely secreted or have transmembrane regions that tether the protein to the cell surface. CRELD1 contains a 333 amino acid acid (aa) extracellular domain (ECD), two tandem transmembrane segments, and a second ECD of 15 aa. Defects in CRELD1 may cause susceptibility to atrioventricular septal defect type 2 which results in a persistent common atrioventricular canal.
Description: A DNA sequence encoding the mouse CRELD1 (NP_598691.1) (Met1-Glu362) was expressed with a C-terminal polyhistidine tag.
Description: A DNA sequence encoding the mouse CRELD1 (NP_598691.1) (Met1-Glu362) was expressed with a C-terminal polyhistidine tag.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
45,718 Da
NCBI Official Full Name
cysteine-rich with EGF-like domain protein 1
NCBI Official Synonym Full Names
cysteine-rich with EGF-like domains 1
NCBI Official Symbol
Creld1
NCBI Official Synonym Symbols
i11E7; AI843811
NCBI Protein Information
cysteine-rich with EGF-like domain protein 1
UniProt Protein Name
Cysteine-rich with EGF-like domain protein 1
Protein Family
UniProt Gene Name
Creld1
Uniprot Description
CRELD1: Defects in CRELD1 may be the cause of susceptibility to atrioventricular septal defect type 2 (AVSD2). AVSD is a spectrum of cardiac malformations that result in a persistent common atrioventricular canal. The complete form of AVSD involves underdevelopment of the lower part of the atrial septum and the upper part of the ventricular septum. A less severe form, known as partial AVSD or ostium primum atrial septal defect has a deficiency of the atrial septum. Complete AVSD are clinically apparent at birth, whereas less severe forms, such as an isolated cleft mitral valve or small defects of the atrial or ventricular septa may go undetected. Belongs to the CRELD family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell adhesion; Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 6 E3|6 52.77 cM
Research Articles on CRELD1
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Product Notes
The CRELD1 creld1 (Catalog #AAA2546644) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant mouse CRELD1 comprises 344 amino acids and has a predicted molecular mass of 37.7 kDa. The apparent molecular mass of the protein is approximately 48 kDa in SDS-PAGE under reducing conditions. Researchers should empirically determine the suitability of the CRELD1 creld1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CRELD1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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