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Mouse anti-Human PTX3/Pentraxin 3/TSG-14 Monoclonal Antibody | anti-PTX3 antibody

Mouse anti Human PTX3/Pentraxin 3/TSG-14 Monoclonal Antibody

Gene Names
PTX3; TSG-14; TNFAIP5
Reactivity
Human
Applications
ELISA
Synonyms
PTX3/Pentraxin 3/TSG-14; Monoclonal Antibody; Mouse anti Human PTX3/Pentraxin 3/TSG-14 Monoclonal Antibody; anti-PTX3 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a
Sequence Length
381
Applicable Applications for anti-PTX3 antibody
ELISA (EIA)
Application Notes
ELISA: 0.5-1 mug/mL. This antibody can be used at 0.5-1 mug/mL with the appropriate secondary reagents to detect Human PTX3. The detection limit for Human PTX3 is approximately 0.039 ng/well.
Immunogen
Recombinant Human PTX3/Pentraxin 3/TSG-14 protein
Buffer
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PTX3/Pentraxin 3/TSG-14 (rh PTX3/Pentraxin 3/TSG-14; NP_002843.2; Met 1-Ser 381). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
Preparation and Storage
This antibody can be stored at 2 degree C- 8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -70 degree C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
41,976 Da
NCBI Official Full Name
pentraxin-related protein PTX3
NCBI Official Synonym Full Names
pentraxin 3
NCBI Official Symbol
PTX3
NCBI Official Synonym Symbols
TSG-14; TNFAIP5
NCBI Protein Information
pentraxin-related protein PTX3
UniProt Protein Name
Pentraxin-related protein PTX3
Protein Family
UniProt Gene Name
PTX3
UniProt Synonym Gene Names
TNFAIP5; TSG14; TNF alpha-induced protein 5; TSG-14
UniProt Entry Name
PTX3_HUMAN

NCBI Description

This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. The protein promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. The protein serves as a biomarker for several inflammatory conditions. [provided by RefSeq, Jun 2016]

Uniprot Description

PTX3: Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self- components and female fertility.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 3q25

Cellular Component: extracellular region; extracellular space

Molecular Function: complement component C1q binding; identical protein binding; protein binding; virion binding

Biological Process: inflammatory response; innate immune response; negative regulation of virion penetration into host cell

Research Articles on PTX3

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Product Notes

The PTX3 ptx3 (Catalog #AAA2543683) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse anti Human PTX3/Pentraxin 3/TSG-14 Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PTX3/Pentraxin 3/TSG-14 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 0.5-1 mug/mL. This antibody can be used at 0.5-1 mug/mL with the appropriate secondary reagents to detect Human PTX3. The detection limit for Human PTX3 is approximately 0.039 ng/well. Researchers should empirically determine the suitability of the PTX3 ptx3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTX3/Pentraxin 3/TSG-14, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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