Mouse anti-Human S100A6 Monoclonal Antibody | anti-S100A6 antibody

Mouse anti Human S100A6 Monoclonal Antibody

Cat. Num. AAA2543516

• Gene Names: S100A6; 2A9; PRA; 5B10; CABP; CACY
• Reactivity: Human
• Applications: Immunocytochemistry, Immunofluorescence, Flow Cytometry, Functional Assay
• Synonyms: S100A6; Monoclonal Antibody; Mouse anti Human S100A6 Monoclonal Antibody; anti-S100A6 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Monoclonal
• Isotype: IgG1
• Sequence Length: 90

• Applicable Applications for anti-S100A6 antibody: Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cyometry (FC/FACS)
• Application Notes: Flow Cytometry: 0.5-2 mug/Test; ICC/IF: 10-25 mug/mL
• Immunogen: Recombinant Human S100A6 protein
• Buffer: 0.2 mum filtered solution in PBS
• Preparation and Storage: This antibody can be stored at 2 degree C- 8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.

NCBI and Uniprot Product Information

• NCBI GI #: 14290498
• NCBI GeneID: 6277
• Molecular Weight: 10,180 Da
• NCBI Official Full Name: S100A6 protein
• NCBI Official Synonym Full Names: S100 calcium binding protein A6
• NCBI Official Symbol: S100A6
• NCBI Official Synonym Symbols: 2A9; PRA; 5B10; CABP; CACY
• NCBI Protein Information: protein S100-A6
• UniProt Protein Name: Protein S100-A6
• Protein Family: Protein
• UniProt Gene Name: S100A6
• UniProt Synonym Gene Names: CACY; PRA
• UniProt Entry Name: S10A6_HUMAN

NCBI Description

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma. [provided by RefSeq, Jul 2008]

Uniprot Description

S100A6: May function as calcium sensor and contribute to cellular calcium signaling (Potential). May function by interacting with other proteins and indirectly play a role in the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative. Belongs to the S-100 family.

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: cytoplasm; cytosol; extrinsic to internal side of plasma membrane; nuclear envelope; nucleus; perinuclear region of cytoplasm; ruffle

Molecular Function: calcium ion binding; calcium-dependent protein binding; protein binding; protein homodimerization activity; tropomyosin binding

Biological Process: signal transduction