Rabbit anti-Human KHDRBS2 Polyclonal Antibody | anti-KHDRBS2 antibody

KHDRBS2 Polyclonal Antibody

Cat. Num. AAA2541686

• Gene Names: KHDRBS2; SLM1; SLM-1
• Reactivity: Human
• Applications: Western Blot, Immunohistochemistry
• Purity: Antigen Affinity Purification
• Synonyms: KHDRBS2; Polyclonal Antibody; KHDRBS2 Polyclonal Antibody; SLM1; SLM-1; bA535F17.1; anti-KHDRBS2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity Purification
• Sequence Length: 349

• Applicable Applications for anti-KHDRBS2 antibody: Western Blot (WB), Immunohistochemistry (IHC)
• Application Notes: WB: 1:500 - 1:1000; IHC: 1:100 - 1:200
• Immunogen: A synthetic peptide of human KHDRBS2
• Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
• Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-9473 / sc-28838
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using KHDRBS2 antibody.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human prostate cancer using KHDRBS2 antibody at dilution of 1:100 (40x lens).)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human esophagus using KHDRBS2 antibody at dilution of 1:100 (40x lens).)

NCBI and Uniprot Product Information

• NCBI GI #: 189217895
• NCBI GeneID: 202559
• NCBI GenBank Nucleotide #: NM_152688.3
• Molecular Weight: 38kDa
• NCBI Official Full Name: KH domain-containing, RNA-binding, signal transduction-associated protein 2
• NCBI Official Synonym Full Names: KH RNA binding domain containing, signal transduction associated 2
• NCBI Official Symbol: KHDRBS2
• NCBI Official Synonym Symbols: SLM1; SLM-1
• NCBI Protein Information: KH domain-containing, RNA-binding, signal transduction-associated protein 2
• UniProt Protein Name: KH domain-containing, RNA-binding, signal transduction-associated protein 2
• Protein Family: KH domain-containing, RNA-binding, signal transduction-associated protein
• UniProt Gene Name: KHDRBS2
• UniProt Synonym Gene Names: SLM1; SLM-1; hSLM-1
• UniProt Entry Name: KHDR2_HUMAN

Uniprot Description

KHDRBS2: RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. Induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. May function as an adapter protein for Src kinases during mitosis. Binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability. Belongs to the KHDRBS family.

Chromosomal Location of Human Ortholog: 6q11.1

Cellular Component: nucleoplasm

Molecular Function: identical protein binding; protein binding