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Western Blot (WB) (Western blot analysis of extracts of various cell lines, using OLFM1 antibody.)

Rabbit OLFM1 Polyclonal Antibody | anti-OLFM1 antibody

OLFM1 Antibody

Gene Names
OLFM1; AMY; NOE1; OlfA; NOELIN1
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
OLFM1; Polyclonal Antibody; OLFM1 Antibody; NOELIN1; AMY; olfactomedin 1; NOE1; Noelin; anti-OLFM1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1mg/mL (varies by lot)
Sequence Length
304
Applicable Applications for anti-OLFM1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Immunogen
Recombinant Protein of human OLFM1
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-165155 / sc-130179
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cell lines, using OLFM1 antibody.)

Western Blot (WB) (Western blot analysis of extracts of various cell lines, using OLFM1 antibody.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human lung cancer using OLFM1 antibody.)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human lung cancer using OLFM1 antibody.)
Related Product Information for anti-OLFM1 antibody
The Olfactomedin family comprises a diverse group of secreted glycoproteins, which includes OLFM1 (Noelin-1), OLFM2 (Noelin-2), OLFM3 (Noelin-3), OLFM4 (Noelin-4), tiarin, pancortin, gliomedin and mycocilin. These proteins are implicated in the development of the nervous system. Specifically, OLFM1 and OLFM2 expression is observed in the neural plate and neural crest, as well as in the cranial ganglia in mouse at E8-10, and later in brain tissue and in the zone of polarizing activity in the limb. Overexpression of OLFM1 causes an excess of neural crest emigrations and prolonged neural crest production. OLFM2 participates in the regulation of the development of the anterior nervous system. An Arg144Gln mutation in OLFM2 has been implicated as a possible cause for open-angle glaucoma (OAG).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
52,815 Da
NCBI Official Full Name
OLFM1 protein, partial
NCBI Official Synonym Full Names
olfactomedin 1
NCBI Official Symbol
OLFM1
NCBI Official Synonym Symbols
AMY; NOE1; OlfA; NOELIN1
NCBI Protein Information
noelin; neuroblastoma protein; neuronal olfactomedin-related ER localized protein; olfactomedin related ER localized protein; olfactomedin-1; pancortin 1
UniProt Protein Name
Noelin
Protein Family
UniProt Gene Name
OLFM1
UniProt Synonym Gene Names
NOE1; NOEL1
UniProt Entry Name
NOE1_HUMAN

NCBI Description

This gene product shares extensive sequence similarity with the rat neuronal olfactomedin-related ER localized protein. While the exact function of the encoded protein is not known, its abundant expression in brain suggests that it may have an essential role in nerve tissue. Several alternatively spliced transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

OLFM1: Seems to play an important role in regulating the production of neural crest cells by the neural tube. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Cell development/differentiation

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: extracellular space; synapse; cell junction

Molecular Function: protein binding; beta-amyloid binding

Biological Process: nervous system development; protein oligomerization

Research Articles on OLFM1

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Product Notes

The OLFM1 olfm1 (Catalog #AAA2520187) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The OLFM1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's OLFM1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the OLFM1 olfm1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OLFM1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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