Goat DEFB107A Polyclonal Antibody | anti-DEFB107A antibody

Goat Polyclonal to Human DEFB107A

Cat. Num. AAA248690

• Gene Names: DEFB107A; BD-7; DEFB-7; DEFB107
• Reactivity: Chimpanzee, Human
• Applications: Immunohistochemistry, ELISA
• Purity: Immunoaffinity Purified
• Synonyms: DEFB107A; Polyclonal Antibody; Goat Polyclonal to Human DEFB107A; Anti-DEFB107A Antibody (Internal) IHC-plus; DEFB107; Beta-defensin 7; BD-7; DEFB-7; Defensin; beta 107A; beta 7; DEFB7; Beta-defensin 107; beta 107; Human DEFB107A; anti-DEFB107A antibody

• Host: Goat
• Reactivity: Chimpanzee, Human
• Clonality: Polyclonal
• Specificity: Human DEFB107A/B.
• Purity/Purification: Immunoaffinity Purified
• Form/Format: Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
• Concentration: 0.5 mg/ml (varies by lot)
• Sequence Length: 70

• Applicable Applications for anti-DEFB107A antibody: Immunohistochemistry (IHC - Paraffin), ELISA (EIA)
• Application Notes: ELISA (1:32000), IHC-P (5 ug/ml); Usage: Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Not tested.
• Target Species: Human
• Immunogen Description: Synthetic peptide HRALISKRMEGHCE from an internal region of human DEFB107A (NP_001032757.2; NP_001035795.1). Percent identity by BLAST analysis: Human, Chimpanzee (100%); Gorilla, Orangutan, Gibbon, Monkey (93%); Marmoset (86%).
• Immunogen Type: Synthetic peptide
• Immunogen: DEFB107A antibody was raised against synthetic peptide HRALISKRMEGHCE from an internal region of human DEFB107A (NP_001032757.2; NP_001035795.1). Percent identity by BLAST analysis: Human, Chimpanzee (100%); Gorilla, Orangutan, Gibbon, Monkey (93%); Marmoset (86%).
• Antigen Modification: Internal
• Preparation and Storage: Store at -20 degree C. Minimize freezing and thawing.

Immunohistochemistry (IHC)

(Anti-DEFB107A antibody IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Product Categories/Family for anti-DEFB107A antibody

Family: New

NCBI and Uniprot Product Information

• NCBI GI #: 103485145
• NCBI GeneID: 245910
• NCBI Accession #: NP_001032757.2
• NCBI GenBank Nucleotide #: NM_001037668.1
• UniProt Accession #: Q8IZN7; Q30E75; Q8NET2; B2RPM1
• Molecular Weight: 7,846 Da
• NCBI Official Full Name: beta-defensin 107
• NCBI Official Synonym Full Names: defensin, beta 107A
• NCBI Official Symbol: DEFB107A
• NCBI Official Synonym Symbols: BD-7; DEFB-7; DEFB107
• NCBI Protein Information: beta-defensin 107; beta-defensin 7; defensin, beta 7
• UniProt Protein Name: Beta-defensin 107
• Protein Family: Beta-defensin
• UniProt Gene Name: DEFB107A
• UniProt Synonym Gene Names: DEFB107; DEFB7; BD-7; DEFB-7
• UniProt Entry Name: D107A_HUMAN

NCBI Description

Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 107, DEFB107A and DEFB107B, in tail-to-tail orientation. This gene, DEFB107A, represents the more centromeric copy. [provided by RefSeq, Oct 2014]

Uniprot Description

DEFB107A: Has antibacterial activity (Potential). Belongs to the beta-defensin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 8p23.1

Cellular Component: extracellular region

Biological Process: defense response to bacterium